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Anthrax Spore Vaccine

This page contains information on Anthrax Spore Vaccine for veterinary use.
The information provided typically includes the following:
  • Anthrax Spore Vaccine Indications
  • Warnings and cautions for Anthrax Spore Vaccine
  • Direction and dosage information for Anthrax Spore Vaccine

Anthrax Spore Vaccine

This treatment applies to the following species:
Company: Colorado Serum

Nonencapsulated Live Culture

GENERAL INFORMATION: Anthrax Spore Vaccine is prepared from a virtually non-pathogenic, nonencapsulated variant strain of B. anthracis. This vaccine is a suspension of viable Bacillus anthracis spores in Saponin. It is tested for purity, identity, dissociation, spore count, and safety prior to release for sale.

Anthrax is caused by Bacillus anthracis. It is highly virulent, and once access to the animal’s body is gained, it multiplies quickly, invades the blood stream and produces a rapidly fatal blood infection. Symptoms of anthrax vary according to the species of animal and the acuteness of the attack. The average period of incubation ranges from 24 hours to as much as 5 days or more. The acute form, most common in cattle, sheep and goats is characterized by its sudden onset and rapidly fatal course. Affected animals may present with sudden staggering, difficult respiration, trembling, collapse with convulsive movements and death, which may also occur without evidence of illness. Swelling sometimes appears in different parts of the body, such as the throat and tongue, particularly in affected swine. Upon or near death, blood may ooze from body openings.

In the presence of oxygen the bacilli form spores which are remarkably tenacious, highly resistant to heat, low temperatures and chemical disinfectants, retaining viability for many years in both soil and water and upon hides or contaminated objects held in storage. Animals of all species are susceptible to anthrax to some degree. Cattle, horses, sheep and goats are those most frequently affected. Swine apparently possess some natural resistance but anthrax does occasionally appear in them. Dogs, cats and wild animals may become infected under some conditions. Mice and guinea pigs are highly susceptible.

DIRECTIONS WHEN TO VACCINATE: Do not vaccinate within 42 days before slaughter.

In those areas where anthrax is known to be a problem, it is advisable to revaccinate annually, approximately 4 weeks prior to the time the disease usually appears.

For control of outbreaks, vaccination of all animals not showing symptoms is recommended. Not all animals will be protected by this procedure, but taking action as suggested may stop further spread of the disease. It is also recommended that animals showing symptoms be isolated and treated with antibiotics as permitted.

Dosage and Administration

Inject 1 ml subcutaneously into each animal. Revaccinate in 2-3 weeks in heavily contaminated areas.

The region of the neck just in front of the shoulder is a convenient site for administering the vaccine to cattle and swine. Sheep and goats should be vaccinated subcutaneously on their side (mid-thorax) halfway between the front and back legs. Horses may be vaccinated subcutaneously in the middle portion of the neck or in the brisket at a time when the animals are not being heavily worked.

A light to moderate swelling may appear at the site of injection. This will disappear after several days.


There is a risk of adverse reactions (progressive edema) in sensitive species, including goats, young and miniature horses and llamas. Consult your veterinarian when considering vaccination of exotic or sensitive species and immunologically immature or stressed animals.

Animals being vaccinated or recently vaccinated should not receive antibiotics, as antibiotics will interfere with effective vaccination.

Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent.

ACCIDENTAL HUMAN EXPOSURE: In the event of accidental human exposure, consult a physician.

OTHER INFORMATION: Store at 2° to 7° C. Do not freeze. Shake well before use. Do not use disinfectants to sterilize equipment. Use entire contents when first opened. Burn, autoclave or chemically disinfect this container and all unused contents.

Conveniently packaged in 10 dose and 50 dose sizes.

USDA Code: 1011.00

U.S. Vet. License No. 188

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216


Contact us for information on other Colorado Serum Company products.

Fine Veterinary Biologicals since 1923.




Order #

10 ml

10 doses


50 ml

50 doses


CPN: 1101000.4

4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
Telephone:   303-295-7527
Order Desk:   800-525-2065
Fax:   303-295-1923
Every effort has been made to ensure the accuracy of the Anthrax Spore Vaccine information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2020 Animalytix LLC. Updated: 2020-10-21