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Advantage II Kitten

This page contains information on Advantage II Kitten for veterinary use.
The information provided typically includes the following:
  • Advantage II Kitten Indications
  • Warnings and cautions for Advantage II Kitten
  • Direction and dosage information for Advantage II Kitten

Advantage II Kitten

This treatment applies to the following species:

for cats

Company: Bayer Animal Health

Once-A-Month Topical Flea Prevention and Treatment for cats

For Use ONLY on Cats 8 Weeks and Older


For the Prevention and Treatment of Flea Infestations on Cats

● Kills all flea life stages

● Controls existing flea infestations on your cat and prevents further infestations

● Kills fleas within 12 hours of application

● Convenient, easy to apply topical solution

● Fragrance-free

● Waterproof

Active Ingredients

% By Weight





Other Ingredients





Advantage II Kitten Caution

Precautionary Statements

Hazards To Humans

Advantage II Kitten Caution

Harmful if swallowed. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and warm water after handling. Keep out of reach of children. Do not contaminate feed or food.


If Swallowed:

● Call a poison control center or doctor immediately for treatment advice.

● Have person sip a glass of water if able to swallow.

● Do not induce vomiting unless told to do so by the poison control center or doctor.

● Do not give anything to an unconscious person.

If In Eyes:

● Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.

● Call a poison control center or doctor for treatment advice.

If On Skin:

● Wash with plenty of soap and water.


Have the product container or label with you when calling a poison control center or doctor, or going for treatment. For medical emergencies call 1-800-422-9874. For customer questions call 1-800-255-6826.


Treat the patient symptomatically.

Hazards To Domestic Animals

For external use only. Do not apply to cats and kittens under 8 weeks of age or weighing less than 2 lbs. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant or nursing cats. Individual sensitivities, while rare, may occur after using ANY pesticide product for cats. If signs persist, or become more severe, consult a veterinarian immediately. If your cat is on medication, consult your veterinarian before using this or any other product.

Side Effects

Monitor your cat after application, Side effects, although very rare, may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as hypersalivation, vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy) occur, consult your veterinarian or call 1-800-422-9874.

Directions For Use

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.


1. Be sure tube is at bottom of pouch.

2. Using scissors, cut the pouch across the top and remove tube.


1. Remove one applicator tube from the package. See “HOW TO OPEN” section

2. Hold applicator tube in an upright position facing away from you and your pet’s face and eyes. Pull cap off tube.

3. Turn the cap around and place other end of cap back on tube.

4. Twist cap to break seal, then remove cap from tube.

5. Part the hair on the neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your cat’s eyes, or allow your cat to ingest this product. The product is bitter tasting and salivation may occur for a short time if the cat licks the product immediately after treatment. Treatment at the base of the skull will minimize the opportunity for the cat to lick the product. Do not allow the product to run off.

6. Discard empty tube as described in Storage and Disposal.

7. Under normal conditions this product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four (4) weeks. Do not retreat more often than once every fourteen (14) days for kittens or once every seven (7) days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

Product Information

The successive feeding activity of fleas on cats frequently elicits a hypersensitivity skin disorder known as flea allergy dermatitis (FAD) or flea bite hypersensitivity. Treatment of cats with Advantage II for cats rapidly kills fleas and reduces the incidence of this condition.

Advantage II for cats kills fleas and may reduce the incidence of this condition.

Advantage II for cats kills the existing fleas on cats within 12 hours. Reinfesting fleas are killed within 2 hours with protection against further flea infestation lasting for up to four (4) weeks. Preexisting pupae in the environment may continue to emerge for six (6) weeks or longer depending upon the climatic conditions.

Fleas, eggs and larvae in the cat’s surroundings are killed following contact with an Advantage II for cats treated cat. Advantage II for cats provides multi-stage flea control effectively breaking all flea life-cycle stages for lasting control of flea populations.

Advantage II for cats kills adult fleas quickly, within 12 hours, inhibits the development of immature flea life stages and prevents them from reaching the biting adult stage.

Advantage II for cats is waterproof and remains effective following a shampoo treatment or after exposure to rain or sunlight.

Apply monthly treatments for optimal control and prevention of fleas.

For consumer questions call 1-800-255-6826.

For medical emergencies call 1-800-422-9874.


● Use only on cats or kittens 8 weeks and older. Do not apply to cats or kittens weighing less than 2 lbs. Do not use on other animals.

● Do not apply more than one (1) tube per treatment, even for large cats.

● Do not have contact or allow children to have contact with treated area until completely dry.


Do not contaminate water, food or feed by storage or disposal.

Pesticide Storage: Store in a cool, dry place inaccessible to children and pets.

Pesticide Disposal and Container Handling: NonrefiIlable container.

If empty: Do not reuse this container. Place in trash or offer for recycling if available.

If partly filled: Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Limited Warranty And Limitation Of Damages

Bayer HealthCare LLC, Animal Health Division warrants that this material conforms to the chemical description on the label. TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY, INCLUDING ANY OTHER EXPRESS OR IMPLIED WARRANTY OF FITNESS OR MERCHANTABILITY, and no agent of Bayer is authorized to do so except in writing with a specific reference to this warranty. Any damages arising from a breach of this warranty shall be limited to direct damages and shall not include consequential commercial damages such as loss of profits or values, etc.

Manufactured For

Bayer HealthCare LLC, Animal Health Division, P.O. Box 390, Shawnee Mission, Kansas 66201 USA

Bayer, the Bayer Cross and Advantage are registered trademarks of Bayer

© 2013 Bayer HealthCare LLC


Made in Germany

Advantage II is protected by the following U.S. patents: 6,232,328 and 6,001,858

ADVANTAGE Kitten - For Cats 8 Weeks and Older and Weighing 2-5 lbs.

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-150

Four 0.0078 fl oz (0.23 mL) Tubes


ADVANTAGE Small Cat - For Cats 8 Weeks and Older and Weighing 5 - 9 lbs.

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-151

Four 0.014 fl oz (0.4 mL) Tubes


Six 0.014 fl oz (0.4 mL) Tubes

ADVANTAGE Large Cat - For Cats 8 Weeks and Older and Weighing Over 9 lbs.

EPA Est. No. 11556-DEU-1 EPA Reg. No. 11556-152

Four 0.027 fl oz (0.8 mL) Tubes


Six 0.027 fl oz (0.8 mL) Tubes

Regulations for product use are established by country. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Before using or dispensing any product, read and carefully observe the label directions.

Distributed by ELANCO US, INC.
Customer Service:   317-276-1262
Technical Service:   800-428-4441
Every effort has been made to ensure the accuracy of the Advantage II Kitten information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2022 Animalytix LLC. Updated: 2021-11-29