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Actogain 45

This page contains information on Actogain 45 for veterinary use.
The information provided typically includes the following:
  • Actogain 45 Indications
  • Warnings and cautions for Actogain 45
  • Direction and dosage information for Actogain 45

Actogain 45

This treatment applies to the following species:
Manufacturer: Zoetis

Ractopamine Hydrochloride

For Use in Feeds For Cattle Fed in Confinement for Slaughter Only

Type A Medicated Article

Do Not Feed Undiluted

Active Drug Ingredient: Ractopamine Hydrochloride - 45.4 g per lb (100 g per kg)

Important: Must be thoroughly mixed into feeds before use. Follow label directions.

Indication: Complete Feed: For increased rate of weight gain, improved feed efficiency and increased carcass leanness in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Top Dress Feed: For increased rate of weight gain and improved feed efficiency in cattle fed in confinement for slaughter during the last 28 to 42 days on feed.

Note: Carcass leanness effects are not an approved indication for use when feeding ractopamine by Top Dress Feeding methods.

Complete Feed

Indications

Appropriate Concentration of Ractopamine in Type C Medicated Feeda

Ractopamine (mg/hd/d)

Increased Rate of Weight Gain, and Improved Feed Efficiency

8.2 to 24.6 g/ton (9 to 27 ppm)

70-430

Improved Rate of Weight Gain, Improved Feed Efficiency, and Increased Carcass Leanness

9.8 to 24.6 g/ton (11 to 27 ppm)

90-430

a Based on 90% Dry Matter Basis

Carcass Measurements

Effect of Ractopaminea

8.2 grams/ton (9 ppm)

16.4 grams/ton (18 ppm)

24.6 grams/ton (27 ppm)

Hot Carcass Weight, lbs

Dressing Percentage, %

NC

b

b

Carcass Percent Fat, %

NC

12th Rib Fat Thickness, in.

NC

NC

NC

Average Rib Eye Area, sq. in.

USDA Yield Grade

NC

NC

c

Marbling Score

NC

NC

NC

Rate of Carcass Lean Gain per Day

NC

Efficiency of Carcass Lean Gain per Day

NC

a The effect of ractopamine on parameters listed in this table is supported by data generated at the doses tested in the clinical field efficacy trials.

NC = No Change, ↑ = increased, ↓ = decreased

b Steers Only

c Reduction indicates an improvement in USDA Yield Grade.

Top Dress Feed

Indications

Appropriate Concentration of Ractopamine in Type C Medicated Feeda

Ractopamine (mg/hd/d)

Increased Rate of Weight Gain and Improved Feed Efficiency

Appropriate Concentration of Ractopamine in a minimum of 1.0 lb. Top Dressed Type C Medicated Feeda (maximum of 800 g/ton)

70-400

a Based on 90% Dry Matter Basis

Inert Ingredients: Ground corncobs.

Mixing Directions (Complete Feed): Thoroughly mix Actogain 45 Type A Medicated Article in a ton of appropriate feed ingredients or diluents according to the table below to obtain the proper concentration in the Type B Medicated Feed (maximum 4,920 g/ton). The following table gives examples of how some Type B Medicated Feed concentrations can be prepared:

Pounds of Actogain 45a To Add Per Ton To Make a Type B Medicated Feed

Resulting Ractopamine Concentration in Type B Medicated Feedb

grams/ton

grams/pound

36.1

1,640

0.82

72.2

3,280

1.64

108.3

4,920

2.46

a Actogain 45 contains 45.4g ractopamine hydrochloride per pound

b Based on 90% Dry Matter Basis

Thoroughly mix Actogain 45 Type A Medicated Article in a ton of complete cattle feed according to the table below to obtain the proper concentration in the Type C Medicated Feed. Prepare an intermediate pre-blend of the premix prior to mixing in a complete feed. Thoroughly mix the required amount in a convenient quantity of feed ingredients then add to the remaining feed ingredients to make one ton of complete feed.

Pounds of Actogain 45a to Add Per Ton To Make a Type C Medicated Feed

Resulting Ractopamine Concentration in Type C Medicated Feedb

0.18

8.2 grams/ton (9 ppm)

0.36

16.4 grams/ton (18 ppm)

0.54

24.6 grams/ton (27 ppm)

a Actogain 45 contains 45.4g ractopamine hydrochloride per pound

b Based on 90% Dry Matter Basis

Mixing Directions (Liquid Type B Feeds): Thoroughly mix Actogain Type A Medicated Article in a ton of appropriate feed ingredients or diluents according to the table below to obtain the proper concentration in the Type B Medicated Feed (maximum 2300 g/ton).

Maintain supplement pH at 4.5 to 7.5. For stored liquid Type B medicated feeds containing ractopamine, recirculate immediately prior to use for not less than 10 minutes, moving not less than 1% of the tank contents per minute from the bottom of the tank to the top. Recirculate daily as described even when not in use.

The following table gives examples of how some Type B Medicated Feed concentrations can be prepared:

Pounds of Actogain 45a To Add per Ton To Make a Liquid Type B Medicated Feed

Resulting Ractopamine Concentration in Liquid Type B Medicated Feed

grams/ton

grams/pound

36.1

1,640

0.82

44.1

2,000

1.00

50.7

2,300

1.15

a Actogain 45 contains 45.4g ractopamine hydrochloride per pound

Mixing Directions for Preparing Type C Medicated Top Dress Feed: Thoroughly mix Actogain 45 Type A Medicated Article in a ton of appropriate feed ingredients or diluents according to the table below to obtain the proper concentration in the Type C Medicated Feed (maximum 800 g/ton). The following table gives examples of how some Type C Medicated Top Dress Feed concentrations can be prepared:

Pounds of Actogain 45a to Add per Ton To Make a Type C Medicated Top Dress Feed

Resulting Ractopamine Concentration in Type C Medicated Top Dress Feedb

Top Dress

grams/ton

grams/pound

mg/pound

2.20

100

0.05

50

4.41

200

0.10

100

6.61

300

0.15

150

8.81

400

0.20

200

17.62

800

0.40

400

a Actogain 45 contains 45.4g ractopamine hydrochloride per pound

b Based on 90% Dry Matter Basis

Directions for Use (Complete Feed): Feed continuously to cattle fed in confinement for slaughter as the sole ration for the last 28 to 42 days on feed.

Directions for Use (Type C Medicated Top Dress Feed): Feed continuously to cattle fed in confinement for slaughter a Type C Medicated Feed containing up to a maximum of 800 g/ton ractopamine (see mixing directions table) to provide 70 to 400 mg/head/day for the last 28 to 42 days on feed. Type C Medicated Top Dress feed must be fed in a minimum of 1.0 lb per head per day to provide 70 to 400 mg/head/day.

Actogain 45 Caution

Not for animals intended for breeding.

NOT FOR HUMAN USE

WARNING: The active ingredient in Actogain, ractopamine hydrochloride, is a beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure. Not for use in humans. Keep out of the reach of children. The Actogain 45 formulation (Type A Medicated Article) poses a low dust potential under usual conditions of handling and mixing. When mixing and handling Actogain, use protective clothing, impervious gloves, protective eye wear, and a NIOSH-approved dust mask. Operators should wash thoroughly with soap and water after handling. If accidental eye contact occurs, immediately rinse eyes thoroughly with water. If irritation persists, seek medical attention. The material safety data sheet contains more detailed occupational safety information. To report adverse effects, access medical information, or obtain additional product information, call 1-888-963-8471.

Store below 25°C (77°F), excursions permitted to 40°C (104°F). Avoid Moisture.

Expiration Date and Lot Number are printed on the bag. Not to be used after the expiry date.

Restricted Drug (California) - Use Only as Directed - ANADA # 200-548, Approved by FDA

Distributed by: Zoetis Inc., Kalamazoo, MI 49007

To report adverse effects, access medical information, or obtain additional product information, call 1-888-963-8471.

Net Weight

Product No.:

 

25 lb (11.34 kg)

1RAC402

3830000

8RAC402 Rev: 07/13

13742501

NAC No.: 3690367.0

ZOETIS INC.
333 PORTAGE STREET, KALAMAZOO, MI, 49007
Telephone:   269-359-4414
Customer Service:   888-963-8471
Website:   www.zoetis.com
Every effort has been made to ensure the accuracy of the Actogain 45 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-08-21

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