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REDUCTIL 10MG CAPSULES

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Assessed against UK PIL dated February 2006
Reductil 10mg Capsules/Ectiva 10mg Capsules/ Sibutramine 10mg Capsules
Reductil 15mg Capsules/Ectiva 15mg Capsules/ Sibutramine 15mg Capsules
(sibutramine hydrochloride monohydrate)
By iwuohak at 5:07 pm, 10/24/06

Final Draft

Your medicine is available as the above three names, but will be referred to as Sibutramine Capsules
throughout this:
PATIENT INFORMATION LEAFLET
Please read this information carefully before you start to take your medicine. It contains all the information
you should need to know. If you have any questions or are not sure about anything, ask your doctor or
pharmacist. Please keep this leaflet in a safe place, you may wish to refer to it again.
ABOUT YOUR MEDICINE:
Your medicine is called Sibutramine Capsules.
Each 10mg capsule contains 10mg of the active ingredient sibutramine hydrochloride monohydrate
equivalent to 8.37mg of sibutramine. Each hard capsule have a blue cap and a yellow body with the letter
10 inscribed on it.
Each 15mg capsule contains 15mg of the active ingredient sibutramine hydrochloride monohydrate
equivalent to 12.55mg of sibutramine. Each hard capsule have a blue cap and a white body with the letter
15 inscribed on it.
Sibutramine Capsules also contain the following inactive ingredients; microcrystalline cellulose, lactose
monohydrate, magnesium stearate, Indigo carmine (E132), gelatin, colloidal anhydrous silica, titanium
dioxide (E171), quinoline yellow (E104), sodium lauryl sulphate, dimeticone, iron oxides and iron hydroxides
(E172), shellac, soyabean lecithin (E322) and titanium dioxide (E172).
Sibutramine Capsules are available as calendar blister packs of 28 capsules.
PL10383/1504 Reductil 10mg Capsules/Ectiva 10mg Capsules/ Sibutramine 10mg Capsules
PL10383/1505 Reductil 15mg Capsules/Ectiva 15mg Capsules/ Sibutramine 15mg Capsules
POM
Sibutramine Capsules are manufactured by BCM Ltd Nottingham NG2 3AA, UK and is procured from
within the EU and repackaged by Product Licence Holder: Primecrown Ltd, 28 Sarum Complex, Uxbridge,
Middlesex UB8 2RZ.
WHY YOU NEED TO TAKE THIS MEDICINE:
Sibutramine Capsules is a medicine to help you loose weight. It works by making you feel satisfied with less
food. It helps control how much you eat. You should still get hungry but feel full with less food than before.
By eating less, it should be easier for you to loose weight even if you haven t been able to before.
Sibutramine Capsules are only part of the story. Loosing weight means changing habits, and changing them
for good. Your doctor and the doctor s team are there to help and will give you regular check-ups.
BEFORE YOU TAKE YOUR MEDICINE:
You should NOT take Sibutramine Capsules if one or more of these points applies to you and you haven t
talked it through with your doctor, talk to your doctor before you start taking Sibutramine Capsules:
If you are allergic to sibutramine or to any of the other ingredients
If you have high blood pressure (more than 145/90), or a history of heart problems, hardening of the
arteries or of strokes.
If you have liver or kidney problems or if you have problems with your prostrate or thyroid or growths
on the adrenal glands (phaeochromocytoma)
If you are pregnant, might become pregnant or you are breast feeding.
If you are over 65, or under 18
If you have ever had anorexia or bulimia
If you have a psychiatric illness, or have taken other medicines in the last fortnight to treat depression
or psychiatric illness.
If you have taken tryptophan for disturbed sleep, or phentermine or diethylpropion (amfepramone) for
weight reduction in the last fortnight.
If you have the eye disease, narrow angle glaucoma (increased pressure in the eye). Ask your doctor
or optician if you think you have glaucoma, but are not sure which type (see also Take special care ).
If you have a history of drug or alcohol problems
JO/Reg/Sibutramine Capsules/New App/PIL/1504-1505/24.10.06 Pg 1 of 4

Assessed against UK PIL dated February 2006




If you have a medical condition that is causing your weight problem
If you have Tourette syndrome (which causes uncontrolled movements and noises).
This medicine contains lactose. If you have been told by your doctor that you have intolerance to some
sugars, contact your doctor before taking this medicine.

Take Special Care:
If any of the points in this list apply to you, you and your doctor need to talk about them as soon as you can,
if you haven t already.
Do NOT give this product to children under 12 years of age.
If you have epilepsy. Sibutramine Capsule may make things worse, and it does not mix with some
medicines for epilepsy. See Taking Sibutramine Capsule with other medicines .
If you have a family history of tics movements or speech that you can t control
If you have the eye disease open angle glaucoma (increased pressure in the eye) or if you are at risk of
this condition (e.g. if other members of your family have had this condition). Ask your doctor or optician if
you think you have glaucoma, but are not sure which type (see also Before you take your medicine ).
If you are at risk of increased fluid pressure within your eye.
If you have a medical condition which means that you are predisposed to bleeding including heavy
periods, bleeding from the stomach or bowel, bleeding from the gums or bruising.
If you are a woman who could get pregnant. You should make sure you take contraceptive
precautions, because you shouldn t use Sibutramine Capsules if you are pregnant.
Women who are pregnant or breast-feeding
Don t take Sibutramine Capsules if you are pregnant, might be pregnant or if you re breast feeding. Ask your
doctor or pharmacist (chemist) for advice.
WHEN TO TAKE YOUR TABLETS:
Checking your blood pressure
You will be in close touch with your doctor s practice while you take Sibutramine Capsules. They will want to
check your progress regularly, measuring your weight, blood pressure and pulse rate. A few people (fewer
than 1 in every 10) find their blood pressure rises when they take Sibutramine Capsules. If your blood
pressure gets too high, your doctor will take you off the medicine.
Sibutramine Capsules and Alcohol
It is best not to drink alcohol during your weight loss programme with Sibutramine Capsules. Alcoholic drinks
(such as beer, cider, wine or spirits are a very common cause of weight gain. So drinking will make it harder
to reach your target.
Driving and Using Machines
Sibutramine Capsules may affect your judgement, thinking or handling skills. If you find this, do not drive or
use any tools or machines.
Taking Sibutramine Capsules with other Medicines
Some medicines do not mix with Sibutramine Capsules. Check this list
If you are taking any of these medicines, talk to a doctor or pharmacist before you take Sibutramine
Capsules:









Some antibiotics, such as rifampicin, erythromycin and clarithromycin.
Some cough, cold, allergy and decongestant medicines: some of these have ingredients that can
raise blood pressure for example ephedrine, pseudoephedrine or xylometazoline. Ask your pharmacist
for advice.
Some epilepsy medicines: carbamazepine, Phenobarbital (phenobarbitone), phenytoin.
The antifungal medicines, ketoconazole or itraconazole.
Some migraine medicines: for example sumatriptan, dihydroergotamine.
Some opioid pain-killers: for example fentanyl, pentazocine, pethidine, dextromethorphan.
Some steroid drugs and drugs which affect the immune system: cyclosporin, dexamethasone.
Anti-coagulants: heparin, warfarin, clopidogrel.

If you are taking antidepressants, or took them in the last two weeks, talk to a doctor or pharmacist before
you take Sibutramine Capsules.

JO/Reg/Sibutramine Capsules/New App/PIL/1504-1505/24.10.06 Pg 2 of 4

Assessed against UK PIL dated February 2006
Types of antidepressants:
Monoamine Oxidase Inhibitors or MAOIs: these include isocarboxazid, phenelzine and tranylcypromine.
Selective Serotonin Re-uptake Inhibitors or SSRIs: these include fluoxetine and paroxetine
Tricyclic antidepressants: these include amitryptiline, dothiepin and lofepramine.
Please tell your doctor or pharmacist about any other medicines you re taking (or recently took). Remember
to mention medicines you bought yourself without a prescription, over the counter.
HOW TO TAKE SIBUTRAMINE CAPSULES:
Getting the dose right
The usual dose
Adults aged 18 to 65:
Take 1 capsule every morning.
Swallow it whole, with a glass of water. Keep to this dose unless your doctor told you something different.
You can take Sibutramine Capsules with or without food.
Don t give Sibutramine Capsules to children.
How long to take it:
You should only take Sibutramine Capsules as part of your weight loss programme. Your doctor s practice
will see you regularly to see how you are doing. If you don t lose weight in the first three months, or if you put
weight on, your doctor may stop prescribing Sibutramine Capsules for you. In any case, Sibutramine
Capsules usually shouldn t be prescribed for more than one year.
WHAT TO DO IF AN OVERDOSE IS TAKEN:
It is always important to follow the recommended dose on the label. If too many tablets are taken by accident
consult your doctor or go to the nearest hospital casualty department immediately. Remember to take this
leaflet or any remaining tablets with you to show the doctor what you have taken.
WHAT TO DO IF YOU MISS A DOSE:
If you miss a dose, take it as soon as you remember, then carry on as before. Do not exceed the stated
dose.
WHEN YOU STOP TAKING YOUR MEDICINE:
It s unusual to get withdrawal symptoms. On rare occasions, some people may get headaches or have
increased appetites once they stop taking the capsules.
AFTER TAKING YOUR MEDICINE:
Like all medicines Sibutramine Capsules can cause side effects in some people.
Most people don t. Most people who get side effects get them early on (in the first four weeks) and find they
wear off over time. Generally, side effects are mild enough for people to decide to carry on taking
Sibutramine Capsules.
The most common side effects. These might affect 10 in every 100 people or more
Digestive system Loss of appetite; constipation; dry mouth.
Other Problems sleeping.
If these effects bother you, talk to a doctor or pharmacist.
Other common side effects
These might affect between 1 and 10 in every 100 people
Heart and circulation Fast heartbeats; palpitations; abnormal heart rhythm; raised blood pressure; hot
flushes.
Digestive system Feeling sick; making piles (haemorrhoids) worse.
Skin Sweating.

JO/Reg/Sibutramine Capsules/New App/PIL/1504-1505/24.10.06 Pg 3 of 4

Assessed against UK PIL dated February 2006
Senses Odd taste.
Other Light-headedness; pins and needles; headaches; feeling anxious.
If your heart rate goes up enough to make you uncomfortable, or if any other effect worries you, talk to a
doctor or pharmacist as soon as you can.
Uncommon side effects
These might affect less than 1 in every 100 people
Liver and kidneys Kidney problems; raised levels of liver enzymes in tests.
Skin Purple rash on legs; bruising.
Other Seizures; blurred vision, depression, suicidal thoughts, feeling restless, hair loss and short term
memory loss, bleeding from the stomach or bowels.
Change in sexual function Impotence and menstrual disorders.
If you get any of these uncommon effects, stop taking Sibutramine Capsules and talk to a doctor
straight away.
Other signs to watch out for
If you get breathing problems, chest pains or swollen ankles while you re taking the capsules, stop
taking Sibutramine Capsules and talk to a doctor straight away.
Allergic reactions including rashes have been reported. In very rare cases difficulty in breathing, fainting
and swelling of the face and throat can occur which may need emergency treatment. These symptoms can
be accompanied by sickness, headache and fever.
If you suffer from these or any other problems and think your medicine may be causing them, tell your doctor
or pharmacist.
Serotonin Syndrome:
A collection of symptoms which can include feeling confused, sweating, shaking, nausea, hallucinations,
sudden jerk of the muscles or a fast heartbeat may be experienced when taken with other medicines that
affect serotonin release such as sumatriptan and antidepressants.
If you notice anything unusual not mentioned in this leaflet, and you think it might be caused by this
medicine, please talk to your doctor or pharmacist.
STORING YOUR MEDICINE:
Do not use after the expiry date printed on the carton, label or blister strip.
Do not store above 25 C. Store in the original package.
KEEP OUT OF THE REACH AND SIGHT OF CHILDREN.
If your doctor tells you to stop taking the tablets, please take them back to the pharmacist for safe disposal.
Only keep them if your doctor tells you to.
If the tablets become discoloured or show any other signs of deterioration, you should seek the advice of
your pharmacist who will tell you what to do.
IMPORTANT:
This medicine is for YOUR use only. It can only be prescribed by a doctor. Never give to anyone else. It may
harm them even if their symptoms are the same as yours.
This leaflet does not contain complete information about your medicine. If you have any questions or are not
sure about anything, ask your doctor or pharmacist who has access to additional information.
Leaflet date:

24.10.2006.

Remember three basic steps
Control what you eat: take in fewer calories
Step up your activity: use up more calories
Keep it realistic: set your target now for the next three months, and make changes you can stick to for
good.
JO/Reg/Sibutramine Capsules/New App/PIL/1504-1505/24.10.06 Pg 4 of 4

Assessed against UK PIL dated February 2006
By iwuohak at 5:18 pm, 10/24/06

Reductil 10mg Capsules/Ectiva 10mg Capsules/ Sibutramine 10mg
Capsules
Reductil 15mg Capsules/Ectiva 15mg Capsules/ Sibutramine 15mg
Capsules
(sibutramine hydrochloride monohydrate)

Your medicine is available as the above three names, but will be referred to as
Sibutramine Capsules throughout this:
PATIENT INFORMATION LEAFLET
Please read this information carefully before you start to take your medicine. It
contains all the information you should need to know. If you have any questions
or are not sure about anything, ask your doctor or pharmacist. Please keep this
leaflet in a safe place, you may wish to refer to it again.
ABOUT YOUR MEDICINE:
Your medicine is called Sibutramine Capsules.
Each 10mg capsule contains 10mg of the active ingredient sibutramine
hydrochloride monohydrate equivalent to 8.37mg of sibutramine. Each hard
capsule have a blue cap and a yellow body with the letter 10 inscribed on it.
Each 15mg capsule contains 15mg of the active ingredient sibutramine
hydrochloride monohydrate equivalent to 12.55mg of sibutramine. Each hard
capsule have a blue cap and a white body with the letter 15 inscribed on it.
Sibutramine Capsules also contain the following inactive ingredients;
microcrystalline cellulose, lactose monohydrate, magnesium stearate, Indigo
carmine (E132), gelatin, colloidal anhydrous silica, titanium dioxide (E171),
quinoline yellow (E104), sodium lauryl sulphate, dimeticone, iron oxides and
iron hydroxides (E172), shellac, soyabean lecithin (E322) and titanium dioxide
(E172).
Sibutramine Capsules are available as calendar blister packs of 28 capsules.
PL10383/1504
PL10383/1505

Reductil 10mg Capsules/Ectiva 10mg Capsules/
Sibutramine 10mg Capsules
Reductil 15mg Capsules/Ectiva 15mg Capsules/
Sibutramine 15mg Capsules
POM

Sibutramine Capsules are manufactured by BCM Ltd Nottingham NG2 3AA,
UK and is procured from within the EU and repackaged by Product Licence
Holder: Primecrown Ltd, 28 Sarum Complex, Uxbridge, Middlesex UB8 2RZ.
WHY YOU NEED TO TAKE THIS MEDICINE:
Sibutramine Capsules is a medicine to help you loose weight. It works by
making you feel satisfied with less food. It helps control how much you eat. You
should still get hungry but feel full with less food than before. By eating less, it
should be easier for you to loose weight even if you haven t been able to before.
Sibutramine Capsules are only part of the story. Loosing weight means
changing habits, and changing them for good. Your doctor and the doctor s
team are there to help and will give you regular check-ups.
BEFORE YOU TAKE YOUR MEDICINE:
You should NOT take Sibutramine Capsules if one or more of these points
applies to you and you haven t talked it through with your doctor, talk to your
doctor before you start taking Sibutramine Capsules:

If you are allergic to sibutramine or to any of the other ingredients

If you have high blood pressure (more than 145/90), or a history of heart
problems, hardening of the arteries or of strokes.
If you have liver or kidney problems or if you have problems with your
prostrate or thyroid or growths on the adrenal glands
(phaeochromocytoma)
If you are pregnant, might become pregnant or you are breast feeding.
If you are over 65, or under 18
If you have ever had anorexia or bulimia
If you have a psychiatric illness, or have taken other medicines in the
last fortnight to treat depression or psychiatric illness.
If you have taken tryptophan for disturbed sleep, or phentermine or
diethylpropion (amfepramone) for weight reduction in the last fortnight.
If you have the eye disease, narrow angle glaucoma (increased
pressure in the eye). Ask your doctor or optician if you think you have
glaucoma, but are not sure which type (see also Take special care ).
If you have a history of drug or alcohol problems
If you have a medical condition that is causing your weight problem
If you have Tourette syndrome (which causes uncontrolled movements
and noises).
JO/Reg/Sibutramine Capsules/Mk Up PIL/1504,1505/241006 Pg 1 of 4

Mock up

Assessed against UK PIL dated February 2006


This medicine contains lactose. If you have been told by your doctor that
you have intolerance to some sugars, contact your doctor before taking
this medicine.

Take Special Care:
If any of the points in this list apply to you, you and your doctor need to talk
about them as soon as you can, if you haven t already.
Do NOT give this product to children under 12 years of age.
If you have epilepsy. Sibutramine Capsule may make things worse, and it
does not mix with some medicines for epilepsy. See Taking Sibutramine
Capsule with other medicines .
If you have a family history of tics movements or speech that you can t
control
If you have the eye disease open angle glaucoma (increased pressure in
the eye) or if you are at risk of this condition (e.g. if other members of your
family have had this condition). Ask your doctor or optician if you think you
have glaucoma, but are not sure which type (see also Before you take
your medicine ).
If you are at risk of increased fluid pressure within your eye.
If you have a medical condition which means that you are predisposed to
bleeding including heavy periods, bleeding from the stomach or bowel,
bleeding from the gums or bruising.
If you are a woman who could get pregnant. You should make sure you
take contraceptive precautions, because you shouldn t use Sibutramine
Capsules if you are pregnant.
Women who are pregnant or breast-feeding
Don t take Sibutramine Capsules if you are pregnant, might be pregnant or if
you re breast feeding. Ask your doctor or pharmacist (chemist) for advice.
WHEN TO TAKE YOUR TABLETS:
Checking your blood pressure
You will be in close touch with your doctor s practice while you take Sibutramine
Capsules. They will want to check your progress regularly, measuring your
weight, blood pressure and pulse rate. A few people (fewer than 1 in every 10)
find their blood pressure rises when they take Sibutramine Capsules. If your
blood pressure gets too high, your doctor will take you off the medicine.
Sibutramine Capsules and Alcohol
It is best not to drink alcohol during your weight loss programme with
Sibutramine Capsules. Alcoholic drinks (such as beer, cider, wine or spirits are
a very common cause of weight gain. So drinking will make it harder to reach
your target.
Driving and Using Machines
Sibutramine Capsules may affect your judgement, thinking or handling skills. If
you find this, do not drive or use any tools or machines.
Taking Sibutramine Capsules with other Medicines
Some medicines do not mix with Sibutramine Capsules. Check this list
If you are taking any of these medicines, talk to a doctor or pharmacist before
you take Sibutramine Capsules:









Some antibiotics, such as rifampicin, erythromycin and clarithromycin.
Some cough, cold, allergy and decongestant medicines: some of these
have ingredients that can raise blood pressure for example ephedrine,
pseudoephedrine or xylometazoline. Ask your pharmacist for advice.
Some epilepsy medicines: carbamazepine, Phenobarbital
(phenobarbitone), phenytoin.
The antifungal medicines, ketoconazole or itraconazole.
Some migraine medicines: for example sumatriptan, dihydroergotamine.
Some opioid pain-killers: for example fentanyl, pentazocine, pethidine,
dextromethorphan.
Some steroid drugs and drugs which affect the immune system:
cyclosporin, dexamethasone.
Anti-coagulants: heparin, warfarin, clopidogrel.

If you are taking antidepressants, or took them in the last two weeks, talk to a
doctor or pharmacist before you take Sibutramine Capsules.
Types of antidepressants:

Monoamine Oxidase Inhibitors or MAOIs: these include isocarboxazid,
phenelzine and tranylcypromine.

Selective Serotonin Re-uptake Inhibitors or SSRIs: these include fluoxetine
and paroxetine

JO/Reg/Sibutramine Capsules/Mk Up PIL/1504,1505/241006 Pg 2 of 4

Assessed against UK PIL dated February 2006


Tricyclic antidepressants: these include amitryptiline, dothiepin and
lofepramine.

Please tell your doctor or pharmacist about any other medicines you re taking
(or recently took). Remember to mention medicines you bought yourself without
a prescription, over the counter.
HOW TO TAKE SIBUTRAMINE CAPSULES:
Getting the dose right
The usual dose
Adults aged 18 to 65:
Take 1 capsule every morning.
Swallow it whole, with a glass of water. Keep to this dose unless your doctor
told you something different. You can take Sibutramine Capsules with or without
food.
Don t give Sibutramine Capsules to children.
How long to take it:
You should only take Sibutramine Capsules as part of your weight loss
programme. Your doctor s practice will see you regularly to see how you are
doing. If you don t lose weight in the first three months, or if you put weight on,
your doctor may stop prescribing Sibutramine Capsules for you. In any case,
Sibutramine Capsules usually shouldn t be prescribed for more than one year.
WHAT TO DO IF AN OVERDOSE IS TAKEN:
It is always important to follow the recommended dose on the label. If too many
tablets are taken by accident consult your doctor or go to the nearest hospital
casualty department immediately. Remember to take this leaflet or any
remaining tablets with you to show the doctor what you have taken.
WHAT TO DO IF YOU MISS A DOSE:
If you miss a dose, take it as soon as you remember, then carry on as before.
Do not exceed the stated dose.
WHEN YOU STOP TAKING YOUR MEDICINE:
It s unusual to get withdrawal symptoms. On rare occasions, some people may
get headaches or have increased appetites once they stop taking the capsules.
AFTER TAKING YOUR MEDICINE:
Like all medicines Sibutramine Capsules can cause side effects in some
people.
Most people don t. Most people who get side effects get them early on (in the
first four weeks) and find they wear off over time. Generally, side effects are
mild enough for people to decide to carry on taking Sibutramine Capsules.
The most common side effects. These might affect 10 in every 100 people
or more
Digestive system Loss of appetite; constipation; dry mouth.
Other Problems sleeping.
If these effects bother you, talk to a doctor or pharmacist.
Other common side effects
These might affect between 1 and 10 in every 100 people
Heart and circulation Fast heartbeats; palpitations; abnormal heart rhythm;
raised blood pressure; hot flushes.
Digestive system Feeling sick; making piles (haemorrhoids) worse.
Skin Sweating.
Senses Odd taste.
Other Light-headedness; pins and needles; headaches; feeling anxious.
If your heart rate goes up enough to make you uncomfortable, or if any other
effect worries you, talk to a doctor or pharmacist as soon as you can.
Uncommon side effects
These might affect less than 1 in every 100 people
Liver and kidneys Kidney problems; raised levels of liver enzymes in tests.
Skin Purple rash on legs; bruising.
JO/Reg/Sibutramine Capsules/Mk Up PIL/1504,1505/241006 Pg 3 of 4

Assessed against UK PIL dated February 2006
Other Seizures; blurred vision, depression, suicidal thoughts, feeling restless,
hair loss and short term memory loss, bleeding from the stomach or bowels.
Change in sexual function Impotence and menstrual disorders.
If you get any of these uncommon effects, stop taking Sibutramine Capsules
and talk to a doctor straight away.
Other signs to watch out for
If you get breathing problems, chest pains or swollen ankles while you re
taking the capsules, stop taking Sibutramine Capsules and talk to a doctor
straight away.
Allergic reactions including rashes have been reported. In very rare cases
difficulty in breathing, fainting and swelling of the face and throat can occur
which may need emergency treatment. These symptoms can be accompanied
by sickness, headache and fever.
If you suffer from these or any other problems and think your medicine may be
causing them, tell your doctor or pharmacist.
Serotonin Syndrome:
A collection of symptoms which can include feeling confused, sweating,
shaking, nausea, hallucinations, sudden jerk of the muscles or a fast heartbeat
may be experienced when taken with other medicines that affect serotonin
release such as sumatriptan and antidepressants.
If you notice anything unusual not mentioned in this leaflet, and you think it
might be caused by this medicine, please talk to your doctor or pharmacist.
STORING YOUR MEDICINE:
Do not use after the expiry date printed on the carton, label or blister strip.
Do not store above 25 C. Store in the original package.
KEEP OUT OF THE REACH AND SIGHT OF CHILDREN.
If your doctor tells you to stop taking the tablets, please take them back to the
pharmacist for safe disposal. Only keep them if your doctor tells you to.
If the tablets become discoloured or show any other signs of deterioration, you
should seek the advice of your pharmacist who will tell you what to do.
IMPORTANT:
This medicine is for YOUR use only. It can only be prescribed by a doctor.
Never give to anyone else. It may harm them even if their symptoms are the
same as yours.
This leaflet does not contain complete information about your medicine. If you
have any questions or are not sure about anything, ask your doctor or
pharmacist who has access to additional information.
Leaflet date:

24.10.2006.

Remember three basic steps

Control what you eat: take in fewer calories

Step up your activity: use up more calories

Keep it realistic: set your target now for the next three months, and make
changes you can stick to for good.

JO/Reg/Sibutramine Capsules/Mk Up PIL/1504,1505/241006 Pg 4 of 4

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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