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Iclusig: 7 things you should know

Medically reviewed by Carmen Pope, BPharm. Last updated on April 4, 2024.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with Iclusig may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Iclusig. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Iclusig interacts with over 490 drugs. Most of these interactions are considered major or moderate. Common medications that may interact with Iclusig include:

Iclusig does not inhibit CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP3A, or CYP2D6 enzymes and does not induce CYP1A2, CYP2B6, or CYP3A enzymes. Iclusig inhibits P-gp, BCRP, and the bile salt export pump (BSEP) but does not inhibit OATP1B1, OATP1B3, OCT1, OCT2, or the organic anion transporters OAT1 and OAT3.

Note that this list is not all-inclusive and includes only common medications that may interact with Iclusig. You should refer to the prescribing information for Iclusig for a complete list of interactions.


Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Iclusig only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2024 Revision date: April 3, 2024.