Xerese Side Effects
Generic Name: acyclovir / hydrocortisone topical
Note: This page contains side effects data for the generic drug acyclovir / hydrocortisone topical. It is possible that some of the dosage forms included below may not apply to the brand name Xerese.
For the Consumer
Applies to acyclovir / hydrocortisone topical: topical application cream
As well as its needed effects, acyclovir / hydrocortisone topical may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking acyclovir / hydrocortisone topical, check with your doctor immediately:Rare
- Burning, itching, redness, rash, swelling, soreness, or tingling at the application site
- change in skin color at the application site
- dryness or flaking of the skin
- flushing or redness of the skin
- unusually warm skin
- Blistering, burning, or crusting of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to acyclovir / hydrocortisone topical: topical cream
During clinical trials, most side effects were local skin reactions and occurred around the application site.[Ref]
Uncommon (0.1% to 1%): Local skin reactions in application site area (including drying or flaking of skin, burning or tingling after application, erythema, pigmentation changes, application site reaction [including signs/symptoms of inflammation])
Frequency not reported: High and cumulative irritation potential[Ref]
A high and cumulative irritation potential under occlusive and semiocclusive conditions was reported during a 21-day cumulative irritation trial.[Ref]
Frequency not reported: Contact allergy, sensitization to hydrocortisone, possible sensitization to drug's base[Ref]
During a photosafety study, one subject developed a contact allergy to propylene glycol (one of the inactive ingredients of the cream base).[Ref]
Frequency not reported: Contact dermatitis[Ref]
1. "Product Information. Xerese (acyclovir-hydrocortisone topical)." Meda Pharmaceuticals, Somerset, NJ.
It is possible that some side effects of Xerese may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Xerese (acyclovir / hydrocortisone topical)
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