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Veltassa Side Effects

Generic Name: patiromer

Note: This page contains side effects data for the generic drug patiromer. It is possible that some of the dosage forms included below may not apply to the brand name Veltassa.

For the Consumer

Applies to patiromer: oral powder for suspension

As well as its needed effects, patiromer (the active ingredient contained in Veltassa) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking patiromer, check with your doctor immediately:

More common:
  • Drowsiness
  • loss of appetite
  • mood or mental changes
  • muscle spasms (tetany) or twitching
  • nausea or vomiting
  • seizures
  • trembling
  • unusual tiredness or weakness

Minor Side Effects

Some patiromer side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Difficulty having a bowel movement (stool)
Less common:
  • Abdominal or stomach discomfort
  • bloated or full feeling
  • diarrhea
  • excess air or gas in the stomach or intestines
  • passing gas

For Healthcare Professionals

Applies to patiromer: oral powder for reconstitution


Common (1% to 10%): Constipation, diarrhea, nausea, abdominal discomfort, flatulence
Uncommon (0.1% to 1%): Vomiting[Ref]


Uncommon (0.1% to 1%): Edema of the lips[Ref]


Common (1% to 10%): Hypomagnesemia, hypokalemia[Ref]


Common (1% to 10%): Approximately 4.7% of patients in clinical trials developed hypokalemia with a serum potassium value less than 3.5 mEq/L. Approximately 9% of patients in clinical trials developed hypomagnesemia with a serum magnesium value less than 1.4 mg/dL.[Ref]


1. "Product Information. Veltassa (patiromer)." Relypsa, Inc., Redwood City, CA.

It is possible that some side effects of Veltassa may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.