Tussinate Side Effects

Generic name: diphenhydramine / hydrocodone / phenylephrine

Note: This document provides detailed information about Tussinate Side Effects associated with diphenhydramine / hydrocodone / phenylephrine. Some dosage forms listed on this page may not apply specifically to the brand name Tussinate.

Applies to diphenhydramine / hydrocodone / phenylephrine: oral suspension extended release, oral syrup.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• pounding heartbeats or fluttering in your chest;

• a light-headed feeling, like you might pass out;

• severe anxiety, confusion, fear;

• painful or difficult urination;

• little or no urinating; or

• dangerously high blood pressure (severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats).

Common side effects may include:

• dizziness, drowsiness;

• mood changes;

• blurred vision; or

• nausea, vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to diphenhydramine/hydrocodone/phenylephrine: oral suspension extended release, oral syrup.

Nervous system adverse events

Nervous system side effects have included lightheadedness, nervousness, dizziness, drowsiness, sedation, mental clouding, headache, insomnia, tremors, weakness, lethargy, hallucinations, convulsions, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, itchy and prickly sensations, and mood changes.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included difficulty swallowing, dry mouth, anorexia, nausea, vomiting, and heartburn.^[Ref]

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesicle sphincters, urinary retention, and dysuria.^[Ref]

Cardiovascular

Cardiovascular side effects have included pallor, tachycardia, palpitations, irregular heart beat, arrhythmias and cardiovascular collapse with hypotension.^[Ref]

Respiratory

Respiratory side effects have included respiratory difficulty and shortness of breath.^[Ref]

Ocular

Ocular side effects have included blurring of vision.^[Ref]

Dermatologic

Dermatologic side effects have included rare reports of dermatitis.^[Ref]

See also:

Further information

Tussinate side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer