Tussinate Interactions
There are 786 drugs known to interact with Tussinate (diphenhydramine / hydrocodone / phenylephrine), along with 28 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 237 are major, 545 are moderate, and 4 are minor.
- View all 786 medications that may interact with Tussinate
- View Tussinate alcohol/food interactions (1)
- View Tussinate disease interactions (28)
Most frequently checked interactions
View interaction reports for Tussinate (diphenhydramine / hydrocodone / phenylephrine) and the medicines listed below.
- acetaminophen
- Advil PM (diphenhydramine / ibuprofen)
- Afrin NoDrip Sinus (oxymetazoline nasal)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- amoxicillin
- Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- benzonatate
- Cheratussin AC (codeine / guaifenesin)
- Claritin (loratadine)
- Coenzyme Q10 (ubiquinone)
- Delsym (dextromethorphan)
- dexamethasone
- ethanol
- guaifenesin
- High Potency B Complex with B12 and C (multivitamin)
- ibuprofen
- levofloxacin
- Medrol Dosepak (methylprednisolone)
- Mucinex (guaifenesin)
- Mucinex DM (dextromethorphan / guaifenesin)
- Mucinex Fast-Max Severe Congestion & Cold (acetaminophen / dextromethorphan / guaifenesin / phenylephrine)
- multivitamin
- Nasonex (mometasone nasal)
- Neoclarityn (desloratadine)
- Paracetamol (acetaminophen)
- Prozac (fluoxetine)
- Restasis (cyclosporine ophthalmic)
- Senokot (senna)
Tussinate alcohol/food interactions
There is 1 alcohol/food interaction with Tussinate (diphenhydramine / hydrocodone / phenylephrine).
Tussinate disease interactions
There are 28 disease interactions with Tussinate (diphenhydramine / hydrocodone / phenylephrine) which include:
- depression
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about Tussinate (diphenhydramine / hydrocodone / phenylephrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.