Tussinate Interactions
There are 787 drugs known to interact with Tussinate (diphenhydramine / hydrocodone / phenylephrine), along with 28 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 237 are major, 546 are moderate, and 4 are minor.
- View all 787 medications that may interact with Tussinate
- View Tussinate alcohol/food interactions (1)
- View Tussinate disease interactions (28)
Most frequently checked interactions
View interaction reports for Tussinate (diphenhydramine / hydrocodone / phenylephrine) and the medicines listed below.
- acetaminophen
- acetaminophen
- Advil PM (diphenhydramine / ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Afrin NoDrip Sinus (oxymetazoline nasal)
- Afrin NoDrip Sinus (oxymetazoline nasal)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- amoxicillin
- amoxicillin
- Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
- Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
- Augmentin (amoxicillin / clavulanate)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- benzonatate
- benzonatate
- Cheratussin AC (codeine / guaifenesin)
- Cheratussin AC (codeine / guaifenesin)
- Claritin (loratadine)
- Claritin (loratadine)
- Coenzyme Q10 (ubiquinone)
- Coenzyme Q10 (ubiquinone)
- Delsym (dextromethorphan)
- Delsym (dextromethorphan)
- dexamethasone
- dexamethasone
- ethanol
- ethanol
Tussinate alcohol/food interactions
There is 1 alcohol/food interaction with Tussinate (diphenhydramine / hydrocodone / phenylephrine).
Tussinate disease interactions
There are 28 disease interactions with Tussinate (diphenhydramine / hydrocodone / phenylephrine) which include:
- depression
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about Tussinate (diphenhydramine / hydrocodone / phenylephrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.