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Tussi-Pres Pediatric Side Effects

Generic name: dextromethorphan / guaifenesin / phenylephrine

Medically reviewed by Last updated on Jan 24, 2022.

Note: This document contains side effect information about dextromethorphan / guaifenesin / phenylephrine. Some dosage forms listed on this page may not apply to the brand name Tussi-Pres Pediatric.

Applies to dextromethorphan / guaifenesin / phenylephrine: oral liquid, oral suspension, oral syrup, oral tablet, oral tablet extended release.


Do not use this medicine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • little or no urination;

  • fast or slow heartbeats;

  • confusion, dizziness, feeling unsteady;

  • nervousness, sleep problems (insomnia);

  • severe nausea or vomiting;

  • severe headache, blurred vision, pounding in your neck or ears;

  • slow breathing; or

  • unusual changes in mood or behavior.

Common side effects may include:

  • diarrhea, constipation;

  • dizziness, drowsiness;

  • sleep problems (insomnia); or

  • feeling nervous, restless, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dextromethorphan/guaifenesin/phenylephrine: oral capsule, oral liquid, oral suspension, oral suspension extended release, oral syrup, oral tablet, oral tablet extended release.


The manufacturer has not provided adverse event information.[Ref]

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1. "Product Information. Presgen B (brompheniramine/dextromethorph/phenylephrine)." KramerNovis (2019):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.