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Tafluprost ophthalmic Side Effects

Medically reviewed by Last updated on Feb 17, 2024.

Applies to tafluprost ophthalmic: ophthalmic solution.

Serious side effects

Along with its needed effects, tafluprost ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tafluprost ophthalmic:

Less common

Other side effects

Some side effects of tafluprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to tafluprost ophthalmic: ophthalmic solution.


Common (1% to 10%): Ocular stinging/irritation, ocular pruritus including allergic conjunctivitis, cataract, dry eye, ocular pain, eyelash darkening, growth of eyelashes, blurred vision, increased lacrimation, eyelid erythema, foreign body sensation in the eyes, photophobia, reduced visual acuity, punctate keratitis, eye discharge, eyelid edema, iris hyperpigmentation, conjunctival/ocular hyperemia

Uncommon (0.1 to 1%): Blepharal pigmentation, asthenopia, conjunctival edema, blepharitis, anterior chamber cells, ocular discomfort, anterior chamber flare, conjunctival pigmentation, conjunctival follicles, allergic conjunctivitis

Very rare (less than 0.01%): Corneal calcification (in association with the use of phosphate containing eye drops in some patients with significantly damaged corneas)

Frequency not reported: Deepening of the eyelid sulcus, iritis/uveitis[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


The most commonly reported side effect was conjunctival/ocular hyperemia.[Ref]


Common (1% to 10%): Urinary tract infection[Ref]


Common (1% to 10%): Cough

Postmarketing reports: Exacerbation of asthma, dyspnea[Ref]


Uncommon (0.1% to 1%): Hypertrichosis of the eyelid[Ref]


Common (1% to 10%): Common cold[Ref]


1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Cerner Multum, Inc. Australian Product Information.

3. Product Information. Zioptan (tafluprost ophthalmic). Merck & Co., Inc. 2012.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.