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Prolastin Side Effects

Generic name: alpha 1-proteinase inhibitor

Medically reviewed by Drugs.com. Last updated on Nov 14, 2023.

Note: This document provides detailed information about Prolastin Side Effects associated with alpha 1-proteinase inhibitor. Some dosage forms listed on this page may not apply specifically to the brand name Prolastin.

Applies to alpha 1-proteinase inhibitor: intravenous powder for solution, intravenous solution.

Serious side effects of Prolastin

Along with its needed effects, alpha 1-proteinase inhibitor (the active ingredient contained in Prolastin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking alpha 1-proteinase inhibitor:

More common

  • bladder pain
  • bloody or cloudy urine
  • body aches or pain
  • chills
  • cough
  • difficult, burning, or painful urination
  • difficulty with breathing
  • ear congestion
  • fever
  • frequent urge to urinate
  • headache
  • loss of voice
  • lower back or side pain
  • runny or stuffy nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness

Rare

  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • blurred vision
  • chest pain
  • cough producing mucus
  • diarrhea
  • difficult or labored breathing
  • dizziness
  • feeling faint, dizzy, or lightheadedness
  • flushing or redness of the skin, especially on the face and neck
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • nervousness
  • noisy breathing
  • pounding in the ears
  • rapid weight gain
  • shivering
  • slow or fast heartbeat
  • sweating
  • tightness in the chest
  • tingling of the hands or feet
  • trouble sleeping
  • unusual weight gain or loss
  • vomiting

Incidence not known

  • confusion
  • difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • hives or skin rash
  • itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

Other side effects of Prolastin

Some side effects of alpha 1-proteinase inhibitor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • feeling of warmth
  • itching skin
  • muscle or bone pain
  • pain or tenderness around the eyes and cheekbones
  • redness of the face, neck, arms, and occasionally, upper chest
  • sudden sweating

Rare

  • back pain
  • bloating
  • change in taste
  • changes in vision
  • fever
  • loss of taste
  • pain
  • redness of the skin
  • sleepiness or unusual drowsiness
  • swelling of the joints
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • welts

For healthcare professionals

Applies to alpha 1-proteinase inhibitor: intravenous powder for injection, intravenous solution.

Respiratory

Nervous system

Other

Cardiovascular

Dermatologic

Gastrointestinal

Hypersensitivity

Hepatic

Musculoskeletal

Local

Genitourinary

Immunologic

References

1. (2018) "Product Information. Aralast NP (alpha 1-proteinase inhibitor)." Baxter I.V. Systems Division

2. (2018) "Product Information. Glassia (alpha 1-proteinase inhibitor)." Baxter Healthcare Corporation

3. (2018) "Product Information. Prolastin-C (alpha 1-proteinase inhibitor)." Grifols USA LLC

Further information

Prolastin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.