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Oxiconazole topical Side Effects

Medically reviewed by Last updated on Jul 30, 2023.

Applies to oxiconazole topical: topical cream, topical lotion.

Serious side effects of Oxiconazole topical

Along with its needed effects, oxiconazole topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking oxiconazole topical:

Less common


  • Blistering, crusting, dryness, or flaking of skin
  • scaling
  • severe redness, soreness, or swelling of skin
  • burning, itching, and pain in hairy areas
  • pus at root of hair
  • skin irritation

Other side effects of Oxiconazole topical

Some side effects of oxiconazole topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

  • Pain
  • skin rash
  • tingling
  • stinging

For Healthcare Professionals

Applies to oxiconazole topical: topical cream, topical lotion.



-Common (1% to 10%): Pruritus, burning

-Uncommon (0.1% to 1%): Irritation, allergic contact dermatitis, folliculitis, erythema, papules, fissure, maceration, rash


-Uncommon (0.1% to 1%): Burning, pruritus, scaling, dyshidrotic eczema[Ref]



-Uncommon (0.1% to 1%): Stinging, nodules


-Uncommon (0.1% to 1%): Stinging, pain[Ref]

Nervous system


-Uncommon (0.1% to 1%): Tingling[Ref]


1. Jegasothy BV, Pakes GE. Oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent. Clin Ther. 1991;13:126-41.

2. Raulin C, Frosch PJ. Contact allergy to oxiconazole. Contact Dermatitis. 1987;16:39-40.

3. Ramelet AA, Walker-Nasir E. One daily application of oxiconazole cream is sufficient for treating dermatomycoses. Dermatologica. 1987;175:293-5.

4. Product Information. Oxistat (oxiconazole topical). Glaxo Wellcome.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.