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Omaveloxolone Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 18, 2024.

Applies to omaveloxolone: oral capsule.

Serious side effects of omaveloxolone

Along with its needed effects, omaveloxolone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking omaveloxolone:

More common side effects

  • back pain
  • bone pain
  • chills
  • cough
  • dark urine
  • decrease in amount of urine
  • diarrhea
  • fast heartbeat
  • fever
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • muscle aches, pains, and spasms
  • nausea or vomiting
  • noisy, rattling, or trouble breathing
  • runny nose
  • shivering
  • sore throat
  • stomach pain, severe
  • sweating
  • swelling of the fingers, hands, feet, or lower legs
  • unusual tiredness or weakness
  • weight gain
  • yellow eyes or skin

Other side effects of omaveloxolone

Some side effects of omaveloxolone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • mouth or throat pain
  • rash

Managing side effects (general information)

For healthcare professionals

Applies to omaveloxolone: oral capsule.

General adverse events

The most common side effects in 20% or more patients were elevated liver enzymes [aspartate aminotransferase (AST)/alanine aminotransferase (ALT)], headache, nausea, abdominal pain, fatigue, diarrhea, and musculoskeletal pain.[Ref]

Dermatologic

Gastrointestinal

Metabolic

Musculoskeletal

Nervous system

Other

References

1. (2023) "Product Information. Skyclarys (omaveloxolone)." Reata Pharmaceuticals, Inc.

Further information

Omaveloxolone side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer