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Notuss-Forte Side Effects

Generic Name: chlorpheniramine / hydrocodone / pseudoephedrine

Note: This document contains side effect information about chlorpheniramine / hydrocodone / pseudoephedrine. Some of the dosage forms listed on this page may not apply to the brand name Notuss-Forte.

For the Consumer

Applies to chlorpheniramine / hydrocodone / pseudoephedrine: oral capsule, oral liquid, oral solution, oral suspension, oral syrup, oral tablet

Along with its needed effects, chlorpheniramine/hydrocodone/pseudoephedrine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking chlorpheniramine/hydrocodone/pseudoephedrine:

More common
  • Fainting
  • lightheadedness
  • shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet
Incidence not known
  • Abdominal or stomach cramps or pain
  • bloating
  • blurred vision
  • bulging soft spot on the head of an infant
  • change in the ability to see colors, especially blue or yellow
  • confusion
  • constipation
  • convulsions
  • decrease in the frequency of urination
  • decrease in the urine volume
  • diarrhea
  • difficult or troubled breathing
  • difficulty in passing urine (dribbling)
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • drowsiness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • irregular, fast or slow, or shallow breathing
  • loss of appetite
  • nervousness
  • painful urination
  • pale or blue lips, fingernails, or skin
  • pounding in the ears
  • shortness of breath
  • sore throat
  • spasm of the throat
  • sweating
  • tightness of the chest
  • unusual tiredness or weakness
  • vomiting

Some side effects of chlorpheniramine/hydrocodone/pseudoephedrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Disturbed color perception
  • double vision
  • dry mouth
  • false or unusual sense of well-being
  • fear or nervousness
  • halos around lights
  • hyperventilation
  • nausea
  • night blindness
  • overbright appearance of lights
  • relaxed and calm
  • restlessness
  • sleepiness or unusual drowsiness
  • sleeplessness
  • trouble sleeping
  • tunnel vision
  • unable to sleep
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Incidence not known
  • Acid or sour stomach
  • belching
  • bigger, dilated, or enlarged pupils (black part of the eye)
  • bloating
  • change in color vision
  • chills
  • cold sweats
  • coma
  • continuing ringing or buzzing or other unexplained noise in the ears
  • cool, pale skin
  • darkened urine
  • depression
  • difficulty seeing at night
  • feeling of constant movement of self or surroundings
  • fever
  • flushing or redness of the skin
  • full feeling
  • hearing loss
  • heartburn
  • hives or welts
  • increased appetite
  • increased hunger
  • increased in sexual ability, desire, drive, or performance
  • increased interest in sexual intercourse
  • increased sensitivity of the eyes to sunlight
  • increased sweating
  • indigestion
  • itching skin
  • loss of appetite
  • nightmares
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pressure in the stomach
  • seizures
  • sensation of spinning
  • skin rash
  • slurred speech
  • stomach discomfort or upset
  • sugar in the urine
  • swelling of the abdominal or stomach area
  • swelling of the breasts or breast soreness in both females and males
  • unusually warm skin
  • watering of the eyes
  • yellow eyes or skin

For Healthcare Professionals

Applies to chlorpheniramine / hydrocodone / pseudoephedrine: oral capsule, oral liquid, oral suspension extended release, oral syrup, oral tablet

General

The more commonly reported adverse effects have included, sedation, somnolence, mental clouding, dizziness, restlessness, nausea and vomiting.[Ref]

Respiratory

Frequency not reported: Dose-related respiratory depression including fatal respiratory depression, dryness of the pharynx, dryness of respiratory passages, laryngismus, wheezing, breathing trouble

Gastrointestinal

Frequency not reported: Nausea, vomiting, constipation, abdominal distension, abdominal pain, acute pancreatitis, dry mouth, dyspepsia, epigastric distress, loss of appetite

Nervous system

Frequency not reported: Sedation, somnolence, drowsiness, lethargy, mental and physical impairment, dizziness, headache, facial dyskinesia, feeling faint, lightheadedness, tremor

Psychiatric

Frequency not reported: Mental clouding, confusion, anxiety, fear, dysphoria, psychic dependence, mood changes, euphoria, agitation, irritability

Genitourinary

Frequency not reported: Ureteral spasm, spasm of vesicle sphincters, urinary retention, dysuria, urinary frequency, urinary hesitancy

Cardiovascular

Frequency not reported: Fast, slow heartbeat, hypertension, hypotension, orthostatic hypotension, palpitations, shock-like state, syncope, feeling faint

Ocular

Frequency not reported: Blurred, double, or other visual disturbances, increased lacrimation, mydriasis, photophobia

Other

Frequency not reported: Labyrinthitis, tinnitus, vertigo

Dermatologic

Frequency not reported: Skin rash, pruritus, erythema, urticaria, excessive perspiration

Endocrine

Frequency not reported: Changes in glucose utilization, decreased lactation, early menses, glycosuria, gynecomastia, hypoglycemia, increased appetite, increased libido, pheochromocytoma stimulation

References

1. "Product Information. Zutripro (chlorpheniramine/hydrocodone/PSE)." Hawthorn Pharmaceuticals, Madison, MS.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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