Nembutal Sodium Side Effects
Generic name: pentobarbital
Medically reviewed by Drugs.com. Last updated on Mar 3, 2022.
Note: This document contains side effect information about pentobarbital. Some of the dosage forms listed on this page may not apply to the brand name Nembutal Sodium.
For the Consumer
Applies to pentobarbital: parenteral solution for injection
Warning
Special Alerts:
A standardized concentration for this drug has been established through Standardize 4 Safety (S4S), a national patient safety initiative to reduce medication errors, especially during transitions of care. The drug is included in a standard concentration list which may apply to an IV or oral compounded liquid formulation. For additional information, see the ASHP website [Web].
Side effects include:
Residual sedation, drowsiness, lethargy, vertigo, nausea, vomiting, headache.
For Healthcare Professionals
Applies to pentobarbital: compounding powder, injectable solution, oral capsule, oral elixir, rectal suppository
Nervous system
Common (1% to 10%): Somnolence
Uncommon (0.1% to 1%): Ataxia, central nervous system (CNS) depression, dizziness, hyperkinesia, syncope
Frequency not reported: Headache[Ref]
Psychiatric
Uncommon (0.1% to 1%): Abnormal thinking, agitation, anxiety, confusion, dizziness, hallucination, nervousness, nightmares, psychiatric disturbance[Ref]
Gastrointestinal
Uncommon (0.1% to 1%): Constipation, nausea, vomiting[Ref]
Respiratory
Uncommon (0.1% to 1%): Apnea, hypoventilation[Ref]
Cardiovascular
Uncommon (0.1% to 1%): Bradycardia, hypotension[Ref]
Hypersensitivity
Frequency not reported: Angioedema, hypersensitivity reactions[Ref]
Dermatologic
Frequency not reported: Exfoliative dermatitis, skin rashes[Ref]
Hematologic
Megaloblastic anemia occurred with chronic phenobarbital use.[Ref]
Frequency not reported: Megaloblastic anemia[Ref]
Hepatic
Frequency not reported: Liver damage[Ref]
Other
Frequency not reported: Fever[Ref]
Local
Frequency not reported: Injection site reactions[Ref]
More about Nembutal Sodium (pentobarbital)
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- Drug class: barbiturates
Patient resources
- Other brands
- Nembutal
Professional resources
Related treatment guides
References
1. "Product Information. Pentobarbital (pentobarbital)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
2. "Product Information. Nembutal Sodium (pentobarbital)" Abbott Pharmaceutical, Abbott Park, IL.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
