Multaq Side Effects

Generic name: dronedarone

Medically reviewed by Drugs.com. Last updated on May 23, 2024.

Note: This document provides detailed information about Multaq Side Effects associated with dronedarone. Some dosage forms listed on this page may not apply specifically to the brand name Multaq.

Applies to dronedarone: oral tablet.

Common side effects of Multaq

Some side effects of dronedarone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Multaq

Along with its needed effects, dronedarone (the active ingredient contained in Multaq) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dronedarone:

For healthcare professionals

Applies to dronedarone: oral tablet.

General adverse events

• Common (1% to 10%): Asthenia, fatigue^[Ref]

Renal

• Frequency not reported: Hypokalemia and hypomagnesemia with potassium-depleting diuretics, serum creatinine increased 10% or more within 5 days after treatment initiation^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, nausea, abdominal pain, vomiting, dyspeptic symptoms
• Frequency not reported: Dysgeusia, ageusia^[Ref]

Dermatologic

• Common (1% to 10%): Rashes (generalized, macular, maculopapular, erythematous), pruritus, eczema, dermatitis, allergic dermatitis
• Uncommon (0.1% to 1%): Photosensitivity^[Ref]

Cardiovascular

• Very common (10% or more): QT prolongation (28%)
• Common (1% to 10%): Bradycardia
• Very rare (less than 0.01%): New or worsening heart failure, atrial flutter with 1:1 atrioventricular conduction^[Ref]

Hepatic

• Frequency not reported: Liver injury, including acute liver failure requiring transplant, serum hepatic enzymes, serum bilirubin increase

Respiratory

• Frequency not reported: Dyspnea, nonproductive cough
• Postmarketing reports: Interstitial lung disease including pneumonitis and pulmonary fibrosis

Genitourinary

• Common (1% to 10%): Urinary tract infection

Hematologic

• Postmarketing reports: Vasculitis, including leukocytoclastic vasculitis

Immunologic

• Postmarketing reports: Anaphylactic reactions including angioedema

Metabolic

• Frequency not reported: Increased serum creatinine^[Ref]

See also:

Further information

Multaq side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer