Ibutilide Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 5, 2020.
For the Consumer
Applies to ibutilide: parenteral solution for injection
- May cause potentially fatal arrhythmias.1 7 Should be administered only by skilled personnel in a setting in which proper equipment (e.g., cardiac monitors, intracardiac pacing, cardioverter/defibrillator) and therapy for sustained VT are available during and after drug administration.1 (See Arrhythmogenic Effects under Cautions.)
- Adequate anticoagulation recommended for patients with atrial fibrillation of more than 2–3 days’ duration.1
- Select patients carefully such that the expected benefits of conversion to sinus rhythm outweigh the immediate risks of ibutilide therapy.1 Use ibutilide when it is likely to offer an advantage compared with alternative management methods for atrial flutter or fibrillation.1 (See Supraventricular Tachyarrhythmias under Uses.)
Side effects include:
Generally well tolerated. Adverse events affecting the cardiovascular system (e.g., arrhythmogenic affects, affects on cardiac conduction, palpitation, hypotension, hypertension), nausea, and headache reported in ≤5.1% of patients.
For Healthcare Professionals
Applies to ibutilide: intravenous solution
Common (1% to 10%): Sustained polymorphic ventricular tachycardia, non-sustained polymorphic ventricular tachycardia, non-sustained monomorphic ventricular tachycardia, atrioventricular block, bundle branch block, ventricular extrasystoles, hypotension/postural hypotension, bradycardia/sinus bradycardia, tachycardia/sinus tachycardia/supraventricular tachycardia, hypertension, QT segment prolonged, palpitation, tachycardia
Common (1% to 10%): Headache
Common (1% to 10%): Nausea[Ref]
Uncommon (0.1% to 1%): Renal failure[Ref]
More about ibutilide
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: group III antiarrhythmics
- Other brands
Related treatment guides
1. "Product Information. Corvert (ibutilide)." Pharmacia and Upjohn, Kalamazoo, MI.
Some side effects may not be reported. You may report them to the FDA.