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Gamifant Side Effects

Generic name: emapalumab

Medically reviewed by Last updated on May 31, 2023.

Note: This document contains side effect information about emapalumab. Some dosage forms listed on this page may not apply to the brand name Gamifant.

Applies to emapalumab: intravenous solution.

Serious side effects of Gamifant

Along with its needed effects, emapalumab (the active ingredient contained in Gamifant) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking emapalumab:

More common

Other side effects of Gamifant

Some side effects of emapalumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to emapalumab: intravenous solution.


Very common (10% or more): Lymphocytosis (12%)[Ref]


Very common (10% or more): Overall infections (NOTE: Reported infections were 41% viral, 35% bacterial, 9% fungal, and 15% not identified) (56%), serious infections (e.g., sepsis, pneumonia, bacteremia, disseminated histoplasmosis, necrotizing fasciitis, viral infections, perforated appendicitis) (32%), cytomegalovirus infection (12%)

Common (1% to 10%): Immunogenicity[Ref]


Very common (10% or more): Infusion-related reactions (27%)[Ref]


Very common (10% or more): Hypokalemia (15%)

Common (1% to 10%): Vomiting[Ref]


Very common (10% or more): Acute kidney injury[Ref]


Very common (10% or more): Couth (12%), tachypnea (12%)

Common (1% to 10%): Dyspnea, epistaxis[Ref]


Very common (10% or more): Pyrexia (24%)

Common (1% to 10%): Asthenia[Ref]


Very common (10% or more): Hypertension (41%), tachycardia (12%)

Common (1% to 10%): Bradycardia, peripheral edema[Ref]


Very common (10% or more): Rash (12%)[Ref]


Very common (10% or more): Constipation (15%), abdominal pain (12%), diarrhea (12%)

Common (1% to 10%): GI hemorrhage[Ref]


1. Product Information. Gamifant (emapalumab). Sobi Inc. 2018.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.