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Firdapse Side Effects

Generic name: amifampridine

Medically reviewed by Drugs.com. Last updated on Mar 8, 2024.

Note: This document provides detailed information about Firdapse Side Effects associated with amifampridine. Some dosage forms listed on this page may not apply specifically to the brand name Firdapse.

Applies to amifampridine: oral tablet.

Serious side effects of Firdapse

Along with its needed effects, amifampridine (the active ingredient contained in Firdapse) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amifampridine:

More common

  • arm or leg pain
  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain or tightness
  • chills
  • cough
  • cough producing mucus
  • diarrhea
  • difficult, burning, or painful urination
  • difficulty breathing or swallowing
  • dizziness
  • fever
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • headache
  • hoarseness
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle pains, spasms, or weakness
  • nausea
  • nervousness
  • pounding in the ears
  • rapid weight gain
  • runny nose
  • shivering
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • sweating
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • trouble sleeping
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting

Other side effects of Firdapse

Some side effects of amifampridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • back pain
  • blindness
  • constipation
  • decreased vision
  • discouragement
  • falls
  • feeling cold
  • feeling sad or empty
  • heartburn
  • irritability
  • lack or loss of strength
  • loss of interest or pleasure
  • pale skin
  • stomach pain
  • trouble concentrating
  • trouble breathing
  • unusual bleeding or bruising

For healthcare professionals

Applies to amifampridine: oral tablet.

Hematologic

Immunologic

Musculoskeletal

Ocular

Metabolic

Psychiatric

Genitourinary

Hepatic

transferase (GGT)[Ref]

Respiratory

Other

Nervous system

Cardiovascular

Dermatologic

Gastrointestinal

References

1. (2018) "Product Information. Firdapse (amifampridine)." Catalyst Pharmaceuticals, Inc.

2. (2021) "Product Information. Ruzurgi (amifampridine)." Medunik Canada

Frequently asked questions

Further information

Firdapse side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.