Skip to Content

Eryzole Side Effects

Generic Name: erythromycin / sulfisoxazole

Note: This document contains side effect information about erythromycin / sulfisoxazole. Some of the dosage forms listed on this page may not apply to the brand name Eryzole.

Applies to erythromycin / sulfisoxazole: oral powder for suspension

Along with its needed effects, erythromycin / sulfisoxazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking erythromycin / sulfisoxazole:

More common
  • Itching
  • skin rash
Less common
  • Aching of joints and muscles
  • difficulty in swallowing
  • nausea or vomiting
  • pale skin
  • redness, blistering, peeling, or loosening of skin
  • skin rash
  • sore throat and fever
  • stomach pain, severe
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin
  • Blood in urine
  • dark or amber urine
  • irregular or slow heartbeat
  • temporary loss of hearing (with kidney disease and high doses)
  • lower back pain
  • pain or burning while urinating
  • pale stools
  • recurrent fainting
  • severe stomach pain
  • swelling of front part of neck

Check with your doctor as soon as possible if any of the following side effects occur while taking erythromycin / sulfisoxazole:

More common
  • Increased sensitivity to sunlight

Some side effects of erythromycin / sulfisoxazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach cramping and discomfort
  • diarrhea
  • headache
  • loss of appetite
  • nausea or vomiting
Less common
  • Sore mouth or tongue

Some side effects of Eryzole may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Eryzole (erythromycin / sulfisoxazole)

Consumer resources

Other brands: Pediazole

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.