Elapegademase Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 7, 2024.

Applies to elapegademase: intramuscular solution.

Precautions

It is very important that your doctor check your or your child's progress closely to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Protect yourself or your child from infections until your immune function is improved, usually after 2 to 6 months of treatment. If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever, chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

Serious side effects of elapegademase

Along with its needed effects, elapegademase may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking elapegademase:

Other side effects of elapegademase

Some side effects of elapegademase may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to elapegademase: intramuscular solution.

General adverse events

The most common adverse effects were cough (50%) and vomiting (33%)^[Ref]

Immunologic

• Very common (10% or more): Influenza (16%), stoma site infection (16%)
• Frequency not reported: Immunogenicity^[Ref]

Local

• Postmarketing reports: Injection site erythema^[Ref]

Musculoskeletal

• Very common (10% or more): Arthralgia (16%)^[Ref]

Ocular

• Very common (10% or more): Conjunctivitis (16%)^[Ref]

Metabolic

• Very common (10% or more): Injection site discomfort (16%), laceration (16%)^[Ref]

Genitourinary

• Very common (10% or more): Groin abscess (16%)^[Ref]

Oncologic

• Postmarketing reports: Lymphomas^[Ref]

Respiratory

• Very common (10% or more): Cough (50%), productive cough (16%), epistaxis (16%), pulmonary haemophilus infection (16%), hemoptysis (16%), nasal edema (16%), upper respiratory tract infection (16%)^[Ref]

Other

• Very common (10% or more): Fatigue (16%), cerumen impaction (16%), ear canal irritation (16%), ear lobe infection (16%), otitis externa (16%)^[Ref]

Hematologic

• Very common (10% or more): Lymphadenopathy (16%)
• Postmarketing reports: Hemolytic anemia, autoimmune hemolytic anemia, thrombocythemia, autoimmune thrombocytopenia^[Ref]

Nervous system

• Very common (10% or more): Asthenia (16%), convulsion (16%), gait disturbance (16%), migraine (16%)^[Ref]

Renal

• Very common (10% or more): Nephrolithiasis (16%)^[Ref]

Dermatologic

• Very common (10% or more): Fungal skin infection (16%), rash (16%), face swelling (16%)
• Postmarketing reports: Urticaria^[Ref]

Gastrointestinal

• Very common (10% or more): Vomiting (33%), abdominal pain upper (16%), dental caries (16%), tooth abscess (16%), tooth extraction (16%), diarrhea (16%), GI infection (16%), hematochezia (16%), nausea (16%), oral candidiasis (16%), oropharyngeal pain (16%)^[Ref]

See also:

Frequently asked questions

• What condition is Revcovi used to treat?

Further information

Elapegademase side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer