Elapegademase Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of elapegademase during breastfeeding. Because elapegademase is a large protein molecule with a molecular weight of about 113,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If elapegademase is required by the mother, it is not a reason to discontinue breastfeeding. Until more data are available, elapegademase should be used with careful monitoring during breastfeeding.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Elapegademase
CAS Registry Number
1709806-75-6
Drug Class
Breast Feeding
Lactation
Enzymes
Enzyme Replacement Therapy
Adenosine Deaminase Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.