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Effervescent Pain Relief Side Effects

Generic name: aspirin/citric acid/sodium bicarbonate

Medically reviewed by Drugs.com. Last updated on Jun 26, 2024.

Note: This document provides detailed information about Effervescent Pain Relief Side Effects associated with aspirin/citric acid/sodium bicarbonate. Some dosage forms listed on this page may not apply specifically to the brand name Effervescent Pain Relief.

Applies to aspirin/citric acid/sodium bicarbonate: oral tablet, oral tablet effervescent.

Serious side effects

Along with its needed effects, aspirin/citric acid/sodium bicarbonate may cause some unwanted effects. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if: too much medicine is taken, the medicine is taken several times a day, or the medicine is taken for more than a few days in a row.

Check with your doctor immediately if any of the following side effects occur while taking aspirin/citric acid/sodium bicarbonate:

Signs of overdose in children

Check with your doctor as soon as possible if any of the following side effects occur while taking aspirin/citric acid/sodium bicarbonate:

Less common or rare

  • bloody or black, tarry stools
  • frequent urge to urinate
  • headache (severe or continuing)
  • increased blood pressure
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • ringing or buzzing in ears (continuing)
  • skin rash, hives, or itching
  • slow breathing
  • swelling of face, fingers, ankles, feet, or lower legs
  • unpleasant taste
  • unusual tiredness or weakness
  • vomiting of blood or material that looks like coffee grounds
  • weight gain (unusual)

Other side effects

Some side effects of aspirin/citric acid/sodium bicarbonate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More about Effervescent Pain Relief (aspirin/citric acid/sodium bicarbonate)

Patient resources

Other brands

Alka-Seltzer Original, Alka-Seltzer Extra Strength

Related treatment guides

Further information

Effervescent Pain Relief side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.