Ecoza Side Effects
Generic name: econazole topical
Medically reviewed by Drugs.com. Last updated on May 13, 2023.
Note: This document contains side effect information about econazole topical. Some dosage forms listed on this page may not apply to the brand name Ecoza.
Applies to econazole topical: topical cream, topical foam.
Serious side effects of Ecoza
Along with its needed effects, econazole topical (the active ingredient contained in Ecoza) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking econazole topical:
Less common
For Healthcare Professionals
Applies to econazole topical: compounding powder, topical cream, topical foam.
Dermatologic
Topical Cream:
-Common (1% to 10%): Pruritus/itching, skin burning sensation/burning, erythema
-Frequency not reported: Pruritic rash
-Postmarketing reports: Angioedema, contact dermatitis, rash, urticaria, blister, skin exfoliation
Vaginal Cream and Pessaries:
-Common (1% to 10%): Pruritus, skin burning sensation
-Uncommon (0.1% to 1%): Rash
-Rare (0.01% to 0.1%): Erythema
-Postmarketing reports: Angioedema, urticaria, contact dermatitis, skin exfoliation[Ref]
Other
Topical Cream:
-Common (1% to 10%): Pain/stinging
-Uncommon (0.1% to 1%): Discomfort, swelling[Ref]
Genitourinary
Vaginal Cream and Pessaries:
-Uncommon (0.1% to 1%): Vulvovaginal burning sensation[Ref]
Local
One patient developed erythematous, edematous, urticarial-like lesions with vesiculation at the site of drug application. Sensitivity to this drug was confirmed by patch testing.[Ref]
Topical Cream:
-Frequency not reported: Lesions with vesiculation at site of application
Topical Foam:
-Uncommon (0.1% to 1%): Application site reactions
Vaginal Cream and Pessaries:
-Postmarketing reports: Application site pain, application site irritation, application site swelling[Ref]
Hypersensitivity
Topical Cream:
-Frequency not reported: Drug sensitivity
-Postmarketing reports: Hypersensitivity
Vaginal Cream and Pessaries:
-Postmarketing reports: Hypersensitivity[Ref]
More about Ecoza (econazole topical)
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- Drug class: topical antifungals
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References
1. Product Information. Spectazole (econazole topical). Apothecon Inc. 2022.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
3. Millikan LE, Galen WK, Gewirtzman GB, Horwitz SN, Landow RK, Nesbitt LT Jr, Roth HL, Sefton J, Day RM. Naftifine cream 1% versus econazole cream 1% in the treatment of tinea cruris and tinea corporis. J Am Acad Dermatol. 1988;18:52-6.
4. Valsecchi R, Tornaghi A, Tribbia G, Cainelli T. Contact dermatitis from econazole. Contact Dermatitis. 1982;8:422.
5. Heel RC, Brogden RN, Speight TM, Avery GS. Econazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1978;16:177-201.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.