Duohist DH Side Effects
Generic Name: chlorpheniramine / dihydrocodeine / phenylephrine
Note: This document contains side effect information about chlorpheniramine / dihydrocodeine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Duohist DH.
For the Consumer
Applies to chlorpheniramine / dihydrocodeine / phenylephrine: oral liquid
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Stop using this medicine and call your doctor at once if you have:
pounding heartbeats or fluttering in your chest;
a light-headed feeling, like you might pass out;
severe anxiety, confusion, fear;
painful or difficult urination;
little or no urinating; or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.
Common side effects may include:
dizziness, drowsiness, headache;
nausea, upset stomach;
blurred vision; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to chlorpheniramine / dihydrocodeine / phenylephrine: oral liquid, oral syrup
General side effects including light-headedness, dizziness, drowsiness, headache, fatigue, and sedation have been among the most frequently reported with opioid use. Confusion, abdominal pain, lassitude, giddiness, increased irritability or excitement (especially in children) have been reported. Hallucinations, severe narcosis, and vivid dreams have been reported rarely.[Ref]
Gastrointestinal side effects including nausea, vomiting, and constipation have been among the most frequently reported with opioid use. Diarrhea, dry mouth, indigestion, anorexia, spasm of biliary tract have been reported.[Ref]
Dermatologic side effects including sweating, pruritus, and skin reactions have been among the most frequently reported with opioid use. Flushing has been reported.[Ref]
Symptoms of dihydrocodeine withdrawal consist of irritability, restlessness, insomnia, diaphoresis, anxiety, and palpitations.[Ref]
Other side effects of dihydrocodeine have included psychological dependence, physical dependence, and tolerance have been reported to develop upon repeated administration.[Ref]
Renal side effects including granulomatous interstitial nephritis and acute renal failure have been reported rarely during dihydrocodeine administration.[Ref]
Cardiovascular side effects including orthostatic hypotension and cardiac palpitations have been reported.[Ref]
Respiratory side effects including respiratory depression have been reported.[Ref]
Ocular side effects including miosis and blurred vision have been reported.[Ref]
Genitourinary side effects including urinary retention have been reported.[Ref]
Hypersensitivity side effects including anaphylactoid reactions have been reported rarely.[Ref]
1. "Product Information. Pancof-PD (chlorpheniramine / dihydrocodeine / phenylephrine)." Pamlab LLC, Mandeville, LA.
Some side effects of Duohist DH may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: upper respiratory combinations
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