DiHydro-PE Side Effects
Generic name: chlorpheniramine / dihydrocodeine / phenylephrine
Note: This document contains side effect information about chlorpheniramine / dihydrocodeine / phenylephrine. Some dosage forms listed on this page may not apply to the brand name DiHydro-PE.
Applies to chlorpheniramine/dihydrocodeine/phenylephrine: oral liquid, oral syrup.
General
General side effects including light-headedness, dizziness, drowsiness, headache, fatigue, and sedation have been among the most frequently reported with opioid use. Confusion, abdominal pain, lassitude, giddiness, increased irritability or excitement (especially in children) have been reported. Hallucinations, severe narcosis, and vivid dreams have been reported rarely.[Ref]
Gastrointestinal
Gastrointestinal side effects including nausea, vomiting, and constipation have been among the most frequently reported with opioid use. Diarrhea, dry mouth, indigestion, anorexia, spasm of biliary tract have been reported.[Ref]
Dermatologic
Dermatologic side effects including sweating, pruritus, and skin reactions have been among the most frequently reported with opioid use. Flushing has been reported.[Ref]
Other
Symptoms of dihydrocodeine withdrawal consist of irritability, restlessness, insomnia, diaphoresis, anxiety, and palpitations.[Ref]
Other side effects of dihydrocodeine have included psychological dependence, physical dependence, and tolerance have been reported to develop upon repeated administration.[Ref]
Renal
Renal side effects including granulomatous interstitial nephritis and acute renal failure have been reported rarely during dihydrocodeine administration.[Ref]
Cardiovascular
Cardiovascular side effects including orthostatic hypotension and cardiac palpitations have been reported.[Ref]
Respiratory
Respiratory side effects including respiratory depression have been reported.[Ref]
Ocular
Ocular side effects including miosis and blurred vision have been reported.[Ref]
Genitourinary
Genitourinary side effects including urinary retention have been reported.[Ref]
Hypersensitivity
Hypersensitivity side effects including anaphylactoid reactions have been reported rarely.[Ref]
More about DiHydro-PE (chlorpheniramine / dihydrocodeine / phenylephrine)
Related treatment guides
References
1. "Product Information. Pancof-PD (chlorpheniramine / dihydrocodeine / phenylephrine)." Alfasigma USA Inc (formerly Pamlab LLC) (2003):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
