Deoxycholic Acid Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 5, 2024.
Applies to deoxycholic acid: subcutaneous solution.
Precautions
Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.
This medicine may cause nerve injury in the jaw. Check with your doctor right away if you have an uneven smile or muscle weakness in the face.
Tell your doctor if you are using an antiplatelet medicine (eg, aspirin) or a blood thinner (eg, warfarin). These medicines may increase the risk of bleeding or bruising in the treatment area.
This medicine may cause injection site reactions (eg, ulcers, necrosis, and infection). Check with your doctor right away if you have pain, redness, swelling, or open sores at the injection site.
Common side effects of deoxycholic acid
Some side effects of deoxycholic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
Less common side effects
Incidence not known
- hair loss at the injection site
Serious side effects of deoxycholic acid
Along with its needed effects, deoxycholic acid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking deoxycholic acid:
Less common side effects
- headache
- muscle weakness in the face
- pain in the mouth or throat
- pounding in the ears
- slow or fast heartbeat
- trouble swallowing
- uneven smile
Incidence not known
- blue-green to black skin discoloration
- cracking of the skin
- fainting
- neck pain
- pain, redness, or sloughing of the skin at the injection site
- swollen, painful, or tender lymph glands in the neck
For healthcare professionals
Applies to deoxycholic acid: subcutaneous solution.
Gastrointestinal adverse events
Local
- Very common (10% or more): Injection site reactions (96%): edema/swelling (87%), hematoma/bruising (72%), pain (70%), numbness (66%), erythema (27%), induration (23%), paresthesia (14%), nodule (13%), pruritus (12%),
- Common (1% to 10%): Injection site reactions: skin tightness, site warmth, marginal mandibular nerve injury
- Frequency not reported: Injection site reactions: hemorrhage, discoloration, urticaria[Ref]
Cardiovascular
- Common (1% to 10%): Hypertension[Ref]
Hematologic
- Frequency not reported: Lymphadenopathy[Ref]
Musculoskeletal
- Frequency not reported: Neck pain[Ref]
Nervous system
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References
1. (2015) "Product Information. Kybella (deoxycholic acid)." Kythera Biopharmaceuticals, Inc.
More about deoxycholic acid
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Further information
Deoxycholic acid side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.