Skip to main content

Daclizumab Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 6, 2025.

Applies to daclizumab: intravenous solution.

Important warnings This medicine can cause some serious health issues

Intravenous route (solution)

Only physicians experienced in immunosuppressive therapy and management of organ transplant recipients should prescribe daclizumab, and they should have complete information requisite for the follow-up of the patient.

Daclizumab should only be administered by healthcare personnel trained in the administration of the drug who have available adequate laboratory and supportive medical resources.

Precautions

If you are continuing your course of therapy with daclizumab after you are discharged from the hospital, it is very important that your doctor check your progress at regular visits. Your doctor will want to do laboratory tests to make sure daclizumab is working properly.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a skin rash; itching; swelling of the face, tongue, and throat; or trouble with breathing after you get the injection.

You may be more likely to get infections while using this medicine. Tell your doctor if you have symptoms of an infection, such as fever or chills. Try to stay away from people with colds, flu, or other infections.

Using this medicine may cause you to have a higher risk of getting cancer of the lymph system. Talk to your doctor if you have concerns about this risk.

Dental—It is important to maintain good dental hygiene and see a dentist regularly for teeth cleaning.

If you are a woman of childbearing age, you should use effective contraception while receiving this medicine.

Serious side effects of daclizumab

Along with its needed effects, daclizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking daclizumab:

Less common side effects

  • chest pain
  • coughing
  • dizziness
  • fever
  • nausea
  • rapid heart rate
  • red, tender, and oozing skin at incision
  • shortness of breath
  • swelling of the feet or lower legs
  • trembling or shaking of the hands or feet
  • vomiting
  • weakness

Rare side effects

  • frequent urination

Other side effects of daclizumab

Some side effects of daclizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

For healthcare professionals

Applies to daclizumab: intravenous solution, subcutaneous solution.

Cardiovascular adverse events

Dermatologic

Gastrointestinal

Hematologic

Hypersensitivity

Respiratory

Psychiatric

Other

Hepatic

Immunologic

See also:

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2016) "Product Information. Zinbryta (daclizumab)." AbbVie US LLC

Frequently asked questions

Further information

Daclizumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.