Cyklokapron Side Effects
Generic name: tranexamic acid
Medically reviewed by Drugs.com. Last updated on Apr 13, 2025.
Note: This document provides detailed information about Cyklokapron Side Effects associated with tranexamic acid. Some dosage forms listed on this page may not apply specifically to the brand name Cyklokapron.
Applies to tranexamic acid: oral tablet.
Other dosage forms:
Serious side effects of Cyklokapron
Along with its needed effects, tranexamic acid (the active ingredient contained in Cyklokapron) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tranexamic acid:
More common side effects
- pale skin
- trouble breathing with exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
Incidence not known
- anxiety
- change in vision
- chest pain or tightness
- confusion
- cough
- difficulty with swallowing
- dizziness or lightheadedness
- fainting
- fast heartbeat
- numbness of the hands
- pain, redness, or swelling in the arm or leg
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- skin rash, hives, or itching
Other side effects of Cyklokapron
Some side effects of tranexamic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
Precautions
It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
Tell your doctor if you are using birth control pills or other types of birth control (eg, patch, vaginal ring, or intrauterine device). You should not use this medication if you are also using combination hormonal contraception because it may increase your chance of having a blood clot, heart attack, or stroke. Your risk is even higher if you are overweight, if you smoke cigarettes, or if you are over 35 years of age.
This medicine may cause serious allergic reactions including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have shortness of breath, trouble breathing, chest tightness, flushing of the face, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
Call your doctor right away if you have any eye problems, such as a change in your vision. Your doctor will want you to have your eyes checked by an ophthalmologist (eye doctor).
If this medicine does not reduce your bleeding after two menstrual cycles or if it seems to stop working, check with your doctor.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
For healthcare professionals
Applies to tranexamic acid: compounding powder, intravenous solution, oral tablet.
Cardiovascular adverse events
- Frequency not reported: Hypotension
- Postmarketing reports: Thromboembolic events[Ref]
Gastrointestinal
- Very common (10% or more): Abdominal pain (over 30%)
- Common (1% to 10%): Nausea, vomiting, diarrhea[Ref]
Hypersensitivity
- Uncommon (0.1% to 1%): Allergic dermatitis
- Postmarketing reports: Anaphylactic shock, allergic skin reactions[Ref]
A case of severe allergic reaction to tranexamic acid was reported involving a subject on her fourth cycle of treatment who experienced dyspnea, tightening of her throat, and facial flushing that required emergency medical treatment.[Ref]
Musculoskeletal
- Very common (10% or more): Back pain, musculoskeletal pain
- Common (1% to 10%): Arthralgia, muscle cramps[Ref]
Nervous system
- Very common (10% or more): Headache, migraine
- Frequency not reported: Seizures
- Postmarketing reports: Dizziness, seizures[Ref]
Ocular
- Rare (less than 0.1%): Retinal artery occlusion
- Postmarketing reports: Chromatopsia, visual impairment[Ref]
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References
1. (2001) "Product Information. Cyklokapron (tranexamic acid)." Pharmacia and Upjohn
2. (2022) "Product Information. Lysteda (tranexamic acid)." Xanodyne Pharmaceuticals Inc
3. (2020) "Product Information. Lysteda (tranexamic acid)." Ferring Pharmaceuticals Inc
4. (2021) "Product Information. Cyklokapron (tranexamic acid)." Pfizer U.S. Pharmaceuticals Group
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Further information
Cyklokapron side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.