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Bexsero Side Effects

Generic Name: meningococcal group B vaccine

Note: This page contains information about the side effects of meningococcal group B vaccine. Some of the dosage forms included on this document may not apply to the brand name Bexsero.

For the Consumer

Applies to meningococcal group B vaccine: intramuscular suspension

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shot caused any side effects.

Becoming infected with meningococcal disease is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

Common side effects may include:

  • headache;

  • feeling tired;

  • muscle pain;

  • chills; or

  • pain where the shot was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1 800 822 7967.

For Healthcare Professionals

Applies to meningococcal group B vaccine: intramuscular suspension

General

The most common adverse events were pain at the injection site, fatigue, erythema, myalgia, headache, and induration.[Ref]

Local

Very common (10% or more): Injection site pain (92.8%), erythema (50%), induration (32%), swelling (21.6%)
Postmarketing reports: Blisters at or around injection site[Ref]

Nervous system

Very common (10% or more): Fatigue (64.4%), headache (56.9%), sleepiness, unusual crying
Uncommon (0.1% to 1%): Seizures (including febrile seizures)
Postmarketing reports: Syncope, vasovagal responses to injection[Ref]

Musculoskeletal

Very common (10% or more): Myalgia (49%), chills (30.3%), arthralgia (21.6%)[Ref]

Gastrointestinal

Very common (10% or more): Nausea (19%), diarrhea (15.2%)
Common (1% to 10%): Vomiting[Ref]

Psychiatric

Very common (10% or more): Irritability[Ref]

Metabolic

Very common (10% or more): Eating disorders[Ref]

Other

Common (1% to 10%): Fever[Ref]

Dermatologic

Common (1% to 10%): Rash
Uncommon (0.1% to 1%): Eczema
Rare (less than 0.1%): Urticaria[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Pallor (rare after booster)
Rare (less than 0.1%): Kawasaki syndrome[Ref]

Hypersensitivity

Very rare (less than 0.01%): Anaphylaxis
Postmarketing reports: Allergic reactions, rash, eye swelling[Ref]

Respiratory

Frequency not reported: Nasopharyngitis[Ref]

References

1. "Product Information. Trumenba (meningococcal group B vaccine)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

2. "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc, Cambridge, MA.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for Bexsero may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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