Benzoyl peroxide / salicylic acid topical Side Effects

For the Consumer

Applies to benzoyl peroxide / salicylic acid topical: topical pad

Benzoyl peroxide and salicylic acid topical can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using this medicine and Get emergency medical help if you have any of these signs of an allergic reaction while taking benzoyl peroxide / salicylic acid topical: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using benzoyl peroxide and salicylic acid topical and call your doctor at once if you have:

• severe skin irritation after using the medicine;

• scaly or peeling skin;

• redness or swelling of treated skin; or

• nausea, vomiting, diarrhea.

Common side effects may include:

• dry skin or mild irritation;

• dizziness; or

• ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to benzoyl peroxide / salicylic acid topical: topical pad

Dermatologic

Excessive drying has been associated with skin peeling, irritation, erythema, and possible edema.^[Ref]

Dermatologic side effects have included allergic contact dermatitis and excessive drying (4%).^[Ref]

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and diarrhea have been reported.^[Ref]

Nervous system

Nervous system side effects including dizziness, loss of hearing, tinnitus, and lethargy have been reported.^[Ref]

Respiratory

Respiratory side effects including hyperpnea have been reported.^[Ref]

Some side effects of benzoyl peroxide / salicylic acid topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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