Skip to main content

Bebulin VH Side Effects

Generic name: factor ix complex

Medically reviewed by Drugs.com. Last updated on Apr 12, 2022.

Note: This document contains side effect information about factor ix complex. Some dosage forms listed on this page may not apply to the brand name Bebulin VH.

Applies to factor ix complex: intravenous powder for injection.

Warning

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Get emergency medical help if you have signs of an allergic reaction: hives or rash; fast heartbeats; chest tightness, wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • sweating and feeling short of breath;

  • a light-headed feeling, like you might pass out;

  • easy bruising, increased bleeding episodes;

  • bleeding from a wound or where the medicine was injected;

  • signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or

  • signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.

Common side effects may include:

  • headache;

  • flushing (warmth, redness, or tingly feeling);

  • nausea, vomiting;

  • fever, chills; or

  • lack of energy.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to factor ix complex: intravenous powder for injection.

General

Adverse reactions may include headache, fever, chills, flushing, nausea, vomiting, tingling, lethargy, urticaria, and manifestations of allergic reactions.[Ref]

Cardiovascular

Frequency not reported: Flushing, hypotension

Postmarketing reports: Thrombosis, deep vein thrombosis, tachycardia[Ref]

Immunologic

Frequency not reported: Allergic reaction

Postmarketing reports: Hypersensitivity reaction, inhibitor antibody development, anaphylactic/anaphylactoid reaction[Ref]

Respiratory

Postmarketing reports: Pulmonary embolism, shortness of breath, dyspnea, bronchospasm, wheezing, cough[Ref]

Dermatologic

Frequency not reported: Urticaria, erythema

Postmarketing reports: Diaphoresis, angioedema, rash, pruritus[Ref]

Hematologic

Postmarketing reports: Disseminated intravascular coagulation[Ref]

Nervous system

Frequency not reported: Headache, tingling, lethargy, dizziness

Postmarketing reports: Thrombotic stroke[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting

Postmarketing reports: Abdominal pain[Ref]

Other

Frequency not reported: Fever, chills

Postmarketing reports: Facial edema[Ref]

Renal

Postmarketing reports: Nephrotic syndrome (following attempted immune tolerance induction)

Local

Postmarketing reports: Infusion site reactions, infusion site pain

References

1. "Product Information. Profilnine (factor IX complex)." Apothecon Inc (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.