Skip to Content

Bebulin VH Side Effects

Generic Name: factor ix complex

Note: This page contains information about the side effects of factor ix complex. Some of the dosage forms included on this document may not apply to the brand name Bebulin VH.

For the Consumer

Applies to factor ix complex: intravenous powder for injection

Get emergency medical help if you have any of these signs of an allergic reaction while taking factor ix complex (the active ingredient contained in Bebulin VH) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using factor IX and call your doctor at once if you have a serious side effect such as:

  • chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;

  • pain, swelling, warmth, or redness in one or both legs;

  • weak or shallow breathing;

  • feeling short of breath;

  • headache, feeling like you might pass out;

  • flushing (warmth, redness, or tingly feeling);

  • fast or slow heart rate;

  • fever, chills, drowsiness, and runny nose followed by skin rash and joint pain 2 weeks later;

  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • easy bruising, increased bleeding episodes; or

  • bleeding from a wound or where the medicine was injected.

Less serious side effects of factor ix complex may include:

  • mild nausea;

  • mild stomach pain; or

  • mild tingly or jittery feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to factor ix complex: intravenous powder for injection


General side effects have included fever and chills.[Ref]


Cardiovascular side effects have included flushing, and changes in pulse rate and blood pressure.[Ref]


Dermatologic side effects have included urticaria.[Ref]


Gastrointestinal side effects have included nausea and vomiting.


Hematologic side effects have included intravascular coagulation, thrombosis, and emboli.[Ref]

Nervous system

Nervous system side effects have included headache, somnolence, lethargy, and tingling.[Ref]


Respiratory side effects have included respiratory distress, chest pain, and cough.[Ref]


1. "Product Information. Proplex T (Factor IX Complex)." Baxter Healthcare/Hyland Immuno, Deerfield, IL.

2. "Product Information. Bebulin VH (Factor IX Complex)." Baxter Healthcare/Hyland Immuno, Deerfield, IL.

3. "Product Information. Profilnine SD (Factor IX Complex)." Grifols Biologicals Inc, Los Angeles, CA.

Not all side effects for Bebulin VH may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.