Basiliximab Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 8, 2024.

Applies to basiliximab: intravenous powder for solution.

Precautions

If you are continuing your course of therapy with basiliximab after you are discharged from the hospital, it is very important that your doctor check your progress at regular visits. Your doctor will want to do laboratory tests to make sure basiliximab is working properly.

It is important to maintain good dental hygiene and see a dentist regularly for teeth cleaning.

If you are a woman of childbearing age, you should use effective contraception while receiving this medicine and for 2 months after treatment with basiliximab is completed.

Serious side effects of basiliximab

Along with its needed effects, basiliximab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking basiliximab:

Other side effects of basiliximab

Some side effects of basiliximab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

See also:

For healthcare professionals

Applies to basiliximab: intravenous powder for injection.

Cardiovascular adverse events

• Very common (10% or more): Peripheral edema (29%), hypertension (27%), general edema (21%)
• Common (1% to 10%): Chest pain, face edema, leg edema, abnormal heart sounds, angina pectoris, cardiac failure, hypotension, arrhythmia, atrial fibrillation, tachycardia
• Postmarketing reports: Capillary leak syndrome^[Ref]

Hematologic

• Very common (10% or more): Anemia (26%)
• Common (1% to 10%): Hematoma, hemorrhage, purpura, thrombocytopenia, thrombosis, polycythemia, leukopenia

Hypersensitivity

• Postmarketing reports: Severe acute hypersensitivity reactions (including anaphylaxis)

Immunologic

• Very common (10% or more): Infection, sepsis
• Postmarketing reports: Cytokine release syndrome

Musculoskeletal

• Common (1% to 10%): Arthralgia, arthropathy, back pain, bone fracture, cramps, hernia, myalgia, leg pain

Ocular

• Common (1% to 10%): Cataract, conjunctivitis, abnormal vision

Metabolic

• Very common (10% or more): Hyperkalemia (22%), hypercholesterolemia (11%), hypokalemia, hyperglycemia, hypophosphatemia, hyperuricemia
• Common (1% to 10%): Acidosis, dehydration, diabetes mellitus, fluid overload, hyperlipidemia, hypertriglyceridemia, hypocalcemia, hypoglycemia, hypomagnesemia, hypoproteinemia, weight increase

Psychiatric

• Very common (10% or more): Insomnia (24%)
• Common (1% to 10%): Agitation, anxiety, depression

Genitourinary

• Very common (10% or more): Urinary tract infection (46%)
• Common (1% to 10%): Unspecified bladder disorders, genital edema, impotence, ureteral disorder, urinary retention, oliguria

Respiratory

• Very common (10% or more): Upper respiratory tract infection (20%), rhinitis, dyspnea
• Common (1% to 10%): Bronchitis, bronchospasm, abnormal chest sounds, coughing, pharyngitis, pneumonia, pulmonary disorder, pulmonary edema, rhinitis, sinusitis
• Postmarketing reports: Respiratory failure

Other

• Very common (10% or more): Pain (42%), fever (20%)
• Common (1% to 10%): Asthenia, malaise

Nervous system

• Very common (10% or more): Headache (24%), tremor (19%)
• Common (1% to 10%): Rigors, dizziness, neuropathy, paresthesia, hypoesthesia

Renal

• Common (1% to 10%): Albuminuria, bladder disorder, dysuria, frequent micturition, hematuria, increased non-protein nitrogen, abnormal renal function, renal tubular necrosis

Dermatologic

• Very common (10% or more): Hypertrichosis, surgical wound complication, acne
• Common (1% to 10%): Cyst, herpes simplex, herpes zoster, hypertrichosis, pruritus, rash, skin disorder, skin ulceration

Endocrine

• Common (1% to 10%): Increased glucocorticoids

Gastrointestinal

• Very common (10% or more): Constipation (48%), nausea (34%), abdominal pain (21%), diarrhea (21%), vomiting (20%), dyspepsia
• Common (1% to 10%): Enlarged abdomen, esophagitis, flatulence, GI disorder, gastroenteritis, GI hemorrhage, gum hyperplasia, melena, moniliasis, ulcerative stomatitis

Further information

Basiliximab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer