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Anti-thymocyte globulin (rabbit) Side Effects

For the Consumer

Applies to anti-thymocyte globulin (rabbit): intravenous powder for solution

In addition to its needed effects, some unwanted effects may be caused by anti-thymocyte globulin (rabbit). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking anti-thymocyte globulin (rabbit), check with your doctor or nurse immediately:

More common:
  • Black, tarry stools
  • bladder pain
  • chest pain
  • chills
  • cloudy or bloody urine
  • cold
  • confusion
  • cough or hoarseness
  • fast heartbeat
  • fever
  • flu-like symptoms
  • frequent urge to urinate
  • high blood pressure
  • irregular or slow heartbeat
  • lower back or side pain
  • numbness or tingling around the lips, hands, or feet
  • painful or difficult urination
  • shortness of breath or troubled breathing
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swollen glands
  • tiredness or weakness
  • unexplained anxiety
  • unusual bleeding or bruising
  • weakness or heaviness of the legs
Less common:
  • Burning or stinging of the skin
  • painful cold sores or blisters on the lips, nose, eyes, or genitals

Minor Side Effects

Some of the side effects that can occur with anti-thymocyte globulin (rabbit) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Abdominal or stomach pain
  • diarrhea
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • loss of strength or energy
  • muscle pain or weakness
  • nausea
  • pain
  • swelling of the ankles, feet, and fingers
  • tightness in the chest
  • unusual weak feeling

For Healthcare Professionals

Applies to anti-thymocyte globulin (rabbit): intravenous powder for injection


General side effects have included chills, fever, infections and pain.[Ref]


Cardiovascular side effects have included hypertension, peripheral edema, tachycardia, pulmonary edema and myocardial infarction.[Ref]


Other side effects have included infections (bacterial, fungal, viral and protozoal), reactivation of infections (particularly cytomegalovirus [CMV]) and sepsis.[Ref]

Nervous system

Nervous system side effects have included headache, malaise, asthenia and dizziness.[Ref]


Hematologic side effects have included leukopenia and thrombocytopenia.[Ref]


Gastrointestinal side effects have included gastrointestinal and oral moniliasis, abdominal pain, nausea, diarrhea and vomiting.[Ref]


Genitourinary side effects have included urinary tract infection and vaginitis.[Ref]


Dermatologic side effects have included herpes simplex infections and rash.[Ref]


Respiratory side effects have included pneumonia, acute respiratory distress syndrome, pulmonary edema and dyspnea.[Ref]


Metabolic side effects have included hyperkalemia.[Ref]


1. "Product Information. Thymoglobulin (anti-thymocyte globulin (rabbit))." Genzyme Corporation, Cambridge, MA.

Not all side effects for anti-thymocyte globulin (rabbit) may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.