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Anadrol-50 Side Effects

Generic name: oxymetholone

Medically reviewed by Drugs.com. Last updated on Feb 2, 2023.

Note: This document contains side effect information about oxymetholone. Some dosage forms listed on this page may not apply to the brand name Anadrol-50.

Applies to oxymetholone: oral tablet.

Warning

You should not use this medicine if you have severe liver or kidney disease, prostate cancer, male breast cancer, or female breast cancer with high levels of calcium in the blood.

Do not use oxymetholone if you are pregnant.

Long-term use of oxymetholone can cause liver tumors or blood-filled cysts in your liver or spleen. Call your doctor at once if you have upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), or rapid weight gain (especially in your face and midsection).

Get emergency medical help if you have any of these signs of an allergic reaction while taking oxymetholone (the active ingredient contained in Anadrol-50) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Long-term use of oxymetholone can cause liver tumors or blood-filled cysts in your liver or spleen. Call your doctor at once if you have:

Also call your doctor at once if you have:

Women receiving oxymetholone may develop male features, which could be irreversible if treatment is continued. If you are a woman taking oxymetholone, tell your doctor right away if you have:

Common side effects in both men and women may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to oxymetholone: oral tablet.

General

The more commonly reported adverse effects of androgen therapy in males is gynecomastia and excessive frequency and duration of penile erections; in women virilization including voice deepening.[Ref]

Cardiovascular

Frequency not reported: Edema with or without congestive heart failure[Ref]

Genitourinary

Frequency not reported: Phallic enlargement and increased frequency of erections (prepubertal); inhibition of testicular function, testicular atrophy and oligospermia, impotence, chronic priapism, epididymitis, bladder irritability and decrease in seminal volume. excessive frequency and duration of penile erections, oligospermia, increased or decreased libido (postpubertal); clitoral enlargement, menstrual irregularities (women); increased or decreased libido (both sexes)[Ref]

Hepatic

Rare (less than 0.1%): Peliosis hepatic, hepatic necrosis and death

Frequency not reported: Cholestatic jaundice, altered liver function[Ref]

Dermatologic

Frequency not reported: Male pattern baldness, acne[Ref]

Musculoskeletal

Frequency not reported: Premature closure of epiphyses in children, muscle spasms[Ref]

Oncologic

Frequency not reported: Hepatocellular neoplasms[Ref]

Hematologic

Frequency not reported: Suppression of clotting factors II, V, VII, and X; bleeding (in patients on concomitant anticoagulant therapy and polycythemia), anemia, leukemia (in patients with aplastic anemia)[Ref]

Endocrine

Frequency not reported: Gynecomastia, virilization (women), hirsutism[Ref]

Metabolic

Frequency not reported: Retention of sodium, chloride, potassium, calcium, phosphates, increased serum cholesterol, hypercalcemia, decreased glucose tolerance[Ref]

Renal

Frequency not reported: Increased creatine and creatine excretion[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting, diarrhea[Ref]

Psychiatric

Frequency not reported: Excitation, insomnia[Ref]

Other

Frequency not reported: Chills[Ref]

References

1. Product Information. Anadrol-50 (oxymetholone). Unimed Pharmaceuticals.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.