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Medically reviewed by Last updated on Aug 17, 2020.


(tole NAF tate)

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Aerosol, External:

Athletes Foot Spray: 1% (150 g) [contains sd alcohol 40]

Tinactin: 1% (150 g)

Aerosol Powder, External:

Jock Itch Spray: 1% (130 g) [contains sd alcohol 40b]

LamISIL AF Defense: 1% (133 g [DSC])

Tinactin: 1% (133 g)

Tinactin Deodorant: 1% (133 g)

Cream, External:

Antifungal: 1% (14.18 g) [odorless]

Fungi-Guard: 1% (15 g)

Fungoid-D: 1% (113 g [DSC]) [contains cetyl alcohol, methylparaben, propylene glycol, propylparaben, trolamine (triethanolamine)]

Medi-First Anti-Fungal: 1% (1 ea [DSC])

Tinactin: 1% (15 g, 30 g)

Tinactin Jock Itch: 1% (15 g [DSC])

Tolnaftate Antifungal: 1% (114 g [DSC]) [contains cetyl alcohol, methylparaben, polysorbate 80, propylene glycol, propylparaben]

Generic: 1% (14 g, 15 g, 20 g, 28 g, 28.3 g, 30 g)

Powder, External:

Anti-Fungal: 1% (45 g)

Podactin: 1% (45 g)

Tinactin: 1% (108 g [DSC])

Generic: 1% (45 g)

Solution, External:

Dr Gs Clear Nail: 1% (18 mL) [contains propylene glycol]

Mycocide Clinical NS: 1% (30 mL) [contains propylene glycol]

The Treatment Formula 3: 1% (15 mL [DSC]) [contains butylparaben, methylparaben, propylparaben, sesame oil]

Tinaspore: 1% (10 mL)

Generic: 1% (10 mL [DSC])

Brand Names: U.S.

  • Anti-Fungal [OTC]
  • Antifungal [OTC]
  • Athletes Foot Spray [OTC]
  • Dr Gs Clear Nail [OTC]
  • Fungi-Guard [OTC]
  • Fungoid-D [OTC] [DSC]
  • Jock Itch Spray [OTC]
  • LamISIL AF Defense [OTC] [DSC]
  • Medi-First Anti-Fungal [OTC] [DSC]
  • Mycocide Clinical NS [OTC]
  • Podactin [OTC]
  • The Treatment Formula 3 [OTC] [DSC]
  • Tinactin Deodorant [OTC]
  • Tinactin Jock Itch [OTC] [DSC]
  • Tinactin [OTC]
  • Tinaspore [OTC]
  • Tolnaftate Antifungal [OTC] [DSC]

Pharmacologic Category

  • Antifungal Agent, Topical


Distorts the hyphae and stunts mycelial growth in susceptible fungi

Onset of Action

24 to 72 hours

Use: Labeled Indications

Treatment of tinea pedis, tinea cruris, tinea corporis; prevention of tinea pedis

Dosing: Adult

Tinea pedis:

Treatment: Topical: Apply twice daily for 4 weeks

Prevention: Topical: Apply once or twice daily

Tinea corporis, treatment: Topical: Apply twice daily for 4 weeks

Tinea cruris, treatment: Topical: Apply twice daily for 2 weeks

Dosing: Geriatric

Refer to adult dosing.

Dosing: Pediatric

Tinea pedis:

Treatment: Children ≥2 years and Adolescents: Topical: Apply twice daily for 4 weeks

Prevention: Children ≥2 years and Adolescents: Topical: Apply once or twice daily.

Tinea corporis, treatment: Children ≥2 years and Adolescents: Topical: Apply twice daily for 4 weeks.

Tinea cruris, treatment: Children ≥2 years and Adolescents: Topical: Apply twice daily for 2 weeks.


Topical: For external use only; avoid contact with eyes. Wash and dry affected area before drug application. For tinea pedis, also apply to spaces between the toes.

Aerosol, aerosol powder: Shake well prior to use.

Drug Interactions

There are no known significant interactions.

Adverse Reactions

The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.

Frequency not defined.

Dermatologic: Contact dermatitis, pruritus, stinging of the skin

Local: Irritation


Concerns related to adverse effects:

• Irritation: Discontinue if sensitivity or irritation occurs.

Special populations:

• Pediatric: Not for self-medication (OTC use) in children <2 years of age.

Other warnings/precautions:

• Appropriate use: For topical use only; avoid contact with eyes. Apply to clean, dry skin. When used for self-medication (OTC use), contact health care provider if condition does not improve within 4 weeks.

Patient Education

What is this drug used for?

• It is used to treat fungal infections of the skin.

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Severe skin irritation

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.

Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine's uses from the patient education leaflet and is not intended to be comprehensive. This limited summary does NOT include all information available about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you receive from the healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please speak with your healthcare provider and review the entire patient education leaflet.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.