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Medically reviewed by Last updated on Sep 9, 2020.


(loe DOKS a mide)

Index Terms

  • Lodoxamide Tromethamine

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution, Ophthalmic:

Alomide: 0.1% (10 mL)

Brand Names: U.S.

  • Alomide

Pharmacologic Category

  • Mast Cell Stabilizer


Mast cell stabilizer that inhibits the in vivo type I immediate hypersensitivity reaction to increase cutaneous vascular permeability associated with IgE and antigen-mediated reactions


Topical: Negligible



Half-Life Elimination

8.5 hours

Use: Labeled Indications

Ocular disorders: Treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis


Hypersensitivity to lodoxamide or any component of the formulation

Dosing: Adult

Ocular disorders: Ophthalmic: Instill 1 to 2 drops in each affected eye 4 times daily

Dosing: Geriatric

Refer to adult dosing.

Dosing: Pediatric

Ocular disorders: Ophthalmic: Children ≥2 years: Refer to adult dosing.


For topical ophthalmic use only, not for injection. Wash hands before use. To avoid contamination, do not touch dropper tip to eyelids or other surfaces when placing drops in eyes. Remove contact lenses prior to administration. Wait 15 minutes or longer before reinserting lenses.


Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

Drug Interactions

There are no known significant interactions.

Adverse Reactions

The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.

>10%: Ophthalmic: Burning sensation of eyes (transient), eye discomfort (transient), stinging of eyes (transient)

1% to 10%:

Central nervous system: Foreign body sensation of eye, headache

Ophthalmic: Blurred vision, crystalline eye deposits, eye pruritus, lacrimation, ocular hyperemia, ocular edema, xerophthalmia

1%, postmarketing, and/or case reports: Asthenopia, blepharitis, chemosis, corneal abrasion, corneal erosion, corneal ulcer, dizziness, drowsiness, dry nose, epitheliopathy, eye pain, keratitis, nausea, ocular warming sensation, skin rash, sneezing, stomach discomfort, swelling of eye


Concerns related to adverse effects:

• Irritation: May cause discomfort or transient burning or stinging upon instillation.

• Ocular effects: May cause temporary blurred vision or other visual disturbances; caution patients to wait until vision clears before driving or operating machinery.

Special populations:

• Contact lens wearers: Contains benzalkonium chloride which may be absorbed by contact lenses; remove contacts prior to administration and wait 15 minutes before reinserting.

Other warnings/precautions:

• Appropriate use: For topical ophthalmic use only; not for injection. To avoid contamination, do not touch dropper tip to eyelids or other surfaces when placing drops in eyes.

Pregnancy Considerations

Adverse events have not been observed in animal reproduction studies following oral administration. The amount of lodoxamide available systemically following ophthalmic administration is below the level of detection.

Patient Education

What is this drug used for?

• It is used to treat eye swelling.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Burning

• Stinging

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Vision changes

• Eye pain

• Severe eye irritation

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.

Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education leaflet and is not intended to be comprehensive. This limited summary does NOT include all information available about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you receive from the healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please speak with your healthcare provider and review the entire patient education leaflet.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.