Cove Migraine Relief
Dosage form: tablet, film coated
Ingredients: ACETAMINOPHEN 250mg, ASPIRIN 250mg, CAFFEINE 65mg
Labeler: THIRTY MADISON INC
NDC code: 71713-101
Medically reviewed by Drugs.com. Last updated on Jun 2, 2025.
Acetaminophen 250 mg
Aspirin 250 mg (NSAID*)
Caffeine 65 mg
*nonsteroidal anti-inflammatory drug
Pain reliever
Pain reliever aid
- •
- treats migraine
Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness.
Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- •
- skin reddening
- •
- blisters
- •
- rash
If a skin reaction occurs, stop use and seek medical help right away.
Allergy alert: Aspirin may cause a severe allergic reaction which may include:
- •
- hives
- •
- facial swelling
- •
- asthma (wheezing)
- •
- shock
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- •
- more than 2 caplets in 24 hours, which is the maximum daily amount
- •
- with other drugs containing acetaminophen
- •
- 3 or more alcoholic drinks every day while using this product
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
- •
- are age 60 or older
- •
- have had stomach ulcers or bleeding problems
- •
- take a blood thinning (anticoagulant) or steroid drug
- •
- take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)
- •
- have 3 or more alcoholic drinks every day while using this product
- •
- take more or for a longer time than directed
Medication overuse headache warning: Headaches may worsen if this product is used for 10 or more days per month.
Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat.
- •
- if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer
- •
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist
- •
- you have never had migraines diagnosed by a health professional
- •
- you have a headache that is different from your usual migraines
- •
- you have the worst headache of your life
- •
- you have fever and stiff neck
- •
- you have headaches beginning after or caused by head injury, exertion, coughing or bending
- •
- you experienced your first headache after the age of 50
- •
- you have daily headaches
- •
- you have a migraine so severe as to require bed rest
- •
- you have liver disease
- •
- stomach bleeding warning applies to you
- •
- you have a history of stomach problems, such as heartburn
- •
- you have high blood pressure, heart disease, liver cirrhosis, or kidney disease
- •
- you are taking a diuretic
- •
- you have asthma
- •
- you have problems or serious side effects from taking pain relievers or fever reducers
- •
- you have vomiting with your migraine headache
- •
- taking a prescription drug for:
- •
- diabetes
- •
- gout
- •
- arthritis
- •
- under a doctor’s care for any serious condition
- •
- taking any other drug
- •
- taking any other product that contains aspirin, acetaminophen, or any other pain reliever/fever reducer
- •
- an allergic reaction occurs. Seek medical help right away.
- •
- you experience any of the following signs of stomach bleeding:
- •
- feel faint
- •
- vomit blood
- •
- have bloody or black stools
- •
- have stomach pain that does not get better
- •
- your migraine is not relieved or worsens after first dose
- •
- new or unexpected symptoms occur
- •
- ringing in the ears or loss of hearing occurs
ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
- •
- do not use more than directed
- •
- adults: take 2 caplets with a glass of water
- •
- if symptoms persist or worsen, ask your doctor
- •
- do not take more than 2 caplets in 24 hours, unless directed by a doctor
- •
- under 18 years of age: ask a doctor
- •
- store at 20°-25°C (68°-77°F)
- •
- close cap tightly after use
- •
- read all product information before using. Keep this box for important information.
carnauba wax, crospovidone, FD&C blue #1 aluminum lake, hypromellose, microcrystalline cellulose, povidone, pregelatinized starch, propylene glycol, saccharin sodium, stearic acid, titanium dioxide
1-800-719-9260
Migraine Relief
Acetaminophen,
Aspirin (NSAID)
Caffeine Tablets
Pain Reliever
Pain Reliever Aid
24 COATED CAPLETS**
**Capsule Shaped Tablets
| COVE MIGRAINE RELIEF
acetaminophen, aspirin, caffeine tablet, film coated |
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| Labeler - THIRTY MADISON INC (080774087) |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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