Skip to Content

Serostim

Generic Name: somatropin (soe ma TROE pin)
Brand Name: Genotropin, Humatrope, Norditropin FlexPro Pen, Nutropin AQ NuSpin 10, Nutropin AQ Pen 10 Cartridge, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive

What is Serostim?

Serostim is a form of human growth hormone important for the growth of bones and muscles.

Serostim is used to treat growth failure in children and adults who lack natural growth hormone. This includes people with with chronic kidney failure, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, short stature at birth with no catch-up growth, and other causes.

Serostim is also used in adults to treat short bowel syndrome, or to prevent severe weight loss related to AIDS.

Serostim may also be used for purposes not listed in this medication guide.

Important Information

You should not use Serostim if you have cancer, diabetic retinopathy, or if you are being treated for Prader-Willi syndrome and you are overweight or have severe breathing problems. You should not use this medicine if you have a serious illness due to lung failure or complications from recent surgery, injury, or medical trauma.

Before taking this medicine

You should not use this medicine if you are allergic to Serostim or benzyl alcohol, or if you have:

  • a serious illness due to lung failure, or complications from recent surgery, injury, or medical trauma;

  • active cancer;

  • eye problems caused by diabetes (diabetic retinopathy); or

  • if you are being treated for Prader-Willi syndrome and you are overweight or have severe breathing problems (including sleep apnea).

To make sure Serostim is safe for you, tell your doctor if you have ever had:

Some brands of Serostim are not expected to harm an unborn baby, including Genotropin, Omnitrope, Saizen, and Serostim.

It is not known whether certain other brands of Serostim will harm an unborn baby, including Humatrope, Norditropin, Nutropin, Zomacton, and Zorbtive.

Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether Serostim passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Serostim?

Your dose and brand of Serostim, and how often you use it will depend on the condition you are treating. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

In some cases, Serostim should not be used in a child. Certain brands of this medicine contain an ingredient that can cause serious side effects or death in very young infants or premature babies. Do not allow an older child to use this medicine without supervision of an adult.

Serostim is injected into a muscle or under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.

Your care provider will show you the best places on your body to inject Serostim. Use a different place each time you give an injection. Do not inject into the same place two times in a row.

Do not shake the medication bottle or you may ruin the medicine. Prepare your dose only when you are ready to give an injection. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

While using Serostim, you may need frequent blood tests. Your growth progress will need to be tested often. Your eyes and your skin may also need to be checked.

If you are being treated for short bowel syndrome, follow the diet plan created for you by your doctor or nutrition counselor to help control your condition. Serostim is not a cure for short bowel syndrome.

If you have Prader-Willi syndrome, your treatment program may also include weight control. Follow your doctor's instructions very closely.

If you use a form of Serostim that comes in a cartridge for use with an injection pen, use only the pen injection system provided with the this medicine brand you use.

Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

How you store this medicine will depend on the Serostim brand and the diluent you are using. After mixing this medicine, you may need to use it right away or you may be able to store it for later use. Read and carefully follow the instructions provided with your medicine about proper storage of this medicine before and after it has been mixed. Ask your pharmacist if you have any questions about proper storage of your medication.

Throw away any Serostim left over after the expiration date on the label has passed.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Call your doctor if you miss more than 3 doses in a row.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause tremors or shaking, cold sweats, increased hunger, headache, drowsiness, weakness, dizziness, fast heartbeat, and nausea. Long-term overdose may cause excessive growth.

What should I avoid while using Serostim?

If you use Zorbtive to treat short bowel syndrome, avoid drinking fruit juices or soda beverages. elor about what types of liquids you should drink while using Zorbtive.

Avoid drinking alcohol if you have short bowel syndrome. Alcohol can irritate your stomach and could make your condition worse.

Serostim side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Serious breathing problems may occur in patients with Prader-Willi syndrome who use Serostim. If you have Prader-Willi syndrome, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring.

Also call your doctor at once if you have:

  • pain in your knees or hips, walking with a limp;

  • ear pain, swelling, warmth, or drainage;

  • numbness or tingling in your wrist, hand, or fingers;

  • severe swelling or puffiness in your hands and feet;

  • pain or swelling in your joints;

  • pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;

  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor, headache, blurred vision;

  • increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or

  • signs of an adrenal gland problem--extreme weakness, severe dizziness, weight loss, changes in skin color, feeling very weak or tired.

Common side effects may include:

  • swelling, rapid weight gain;

  • muscle or joint pain;

  • stomach pain, gas;

  • headache; or

  • pain, itching, or skin changes where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Serostim?

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with somatropin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your pharmacist can provide more information about Serostim.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 14.01.

Date modified: February 01, 2018
Last reviewed: November 21, 2017

Hide