Naturally occurring growth hormone (somatotropin) is synthesized and stored in the anterior pituitary gland in the brain. Its release is controlled by opposing actions of growth-hormone releasing hormone and somatostatin.
Growth hormone promotes the growth of long bones in the limbs and increases protein synthesis. A synthetic version of growth hormone, somatropin, is available to treat disorders of growth hormone production or deficiency. It is used to treat growth failure in children.
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