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GlucaGen HypoKit (injection)

Generic name: glucagon (injection) [ GLOO-ka-gon ]
Brand names: GlucaGen, GlucaGen HypoKit, Glucagon Emergency Kit for Low Blood Sugar, Gvoke HypoPen, Gvoke PFS
Drug class: Glucose elevating agents

Medically reviewed by on Oct 6, 2023. Written by Cerner Multum.

What is GlucaGen HypoKit?

GlucaGen HypoKit is a hormone that increases blood sugar levels. It also slows involuntary muscle movements of the stomach and intestines that aid in digestion.

GlucaGen HypoKit is used to treat hypoglycemia (low blood sugar). This medicine is also used during a radiologic (x-ray) examination to help diagnose certain disorders of the stomach or intestines.

GlucaGen HypoKit may also be used for purposes not listed in this medication guide.

GlucaGen HypoKit side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of the following skin changes on your face, legs, groin, or genital area:

Common side effects of GlucaGen HypoKit may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


GlucaGen HypoKit should be used to treat hypoglycemia only if the person cannot eat, passes out, or is having a seizure. Be sure you know how to give a this medicine before you need to use it. Hypoglycemia should be treated as quickly as possible. Having low blood sugar for too long can cause seizure, coma, or death.

You should not use GlucaGen HypoKit if you are allergic to GlucaGen HypoKit or lactose, or if you have a tumor of the pancreas (insulinoma) or adrenal gland (pheochromocytoma).

Before taking this medicine

You should not use this medicine if you are allergic to GlucaGen HypoKit or lactose, or if you have:

GlucaGen HypoKit should be used to treat hypoglycemia only if the person is unable to eat, or is unconscious or having a seizure.

Tell your doctor if:

Do not give this medicine to a child without medical advice.

GlucaGen HypoKit is not expected to harm an unborn baby, but quickly treating hypoglycemia would outweigh any risks posed by using this medicine.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

How should I use GlucaGen HypoKit?

Hypoglycemia should be treated as quickly as possible. Having low blood sugar for too long can cause seizure, coma, or death.

GlucaGen HypoKit is injected under the skin, into a muscle, or into a vein. You will be shown how to use emergency this medicines for severe hypoglycemia. Call your doctor after each time you use a this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Be sure you know how to give a GlucaGen HypoKit before you need to use it. The correct dose for a child is lower than an adult dose. A child's dose may also be based on how much the child weighs. Follow your doctor's dosing instructions very carefully.

You may need to mix GlucaGen HypoKit with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

After the injection, you should eat a fast-acting source of sugar (fruit juice, glucose gel, hard candy, raisins, or non-diet soda) and then eat a snack or small meal such as cheese and crackers or a meat sandwich.

If you are a caregiver, get emergency medical help after giving a GlucaGen HypoKit. If the patient does not improve within 15 minutes, you may need to mix a new dose and give a second injection.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

To keep from having severe hypoglycemia, follow your diet, medication, and exercise routines very closely.

Store GlucaGen HypoKit and any diluent at room temperature, away from moisture, heat, and light. Do not refrigerate or freeze. Throw away any mixed medicine you have not used right away. Do not use GlucaGen HypoKit after the expiration date on the label has passed.

Store the auto-injector or prefilled syringe in the foil pouch and use the medicine right away after opening.

What happens if I miss a dose?

Since GlucaGen HypoKit is used as needed, it does not have a daily dosing schedule.

Call your doctor promptly if symptoms do not improve after using GlucaGen HypoKit.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, diarrhea, rapid pulse, or high blood pressure (severe headache, blurred vision, pounding in your neck or ears).

What should I avoid after using GlucaGen HypoKit?

Avoid drinking alcohol. It can lower your blood sugar.

What other drugs will affect GlucaGen HypoKit?

Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of medicines used to treat diabetes. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all medicines you start or stop using.

Popular FAQ

Glucagon is usually given in an emergency to people with insulin-dependent diabetes who develop very low blood sugar levels and pass out or are unable to take some form of sugar by mouth. Glucagon injection or nasal powder (Baqsimi) increases low blood sugar levels back to normal. Continue reading

More FAQ

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.