Skip to Content

Demser

Generic Name: metyrosine (me TYE roe seen)
Brand Name: Demser

Medically reviewed on December 15, 2017

What is Demser?

Demser is used to treat pheochromocytoma (tumor of the adrenal gland).

Demser is given before surgery to control pheochromocytoma, and is also given when surgery is not possible.

Demser may also be used for other purposes not listed in this medication guide.

Important Information

Demser can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of metyrosine.

Call your doctor at once if you have confusion, trouble speaking, tremors, drooling, diarrhea, or painful urination.

Drink plenty of fluid every day--at least six to eight full glasses (8 ounces)--to prevent Demser crystals from forming in your urine.

Before taking this medicine

You should not use this medication if you are allergic to Demser.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

It is not known whether Demser is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether metyrosine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Demser?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take Demser with a full glass of water. Drink 6 to 8 full glasses of water while you are taking Demser. This will help keep crystals from forming in your urine.

Store Demser at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of Demser.

Overdose symptoms may include extreme drowsiness, anxiety, tremors, or tightness of your jaw.

What should I avoid while taking Demser?

Demser can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of metyrosine.

Demser side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • drooling;

  • difficulty speaking;

  • tremors;

  • muscle spasms;

  • disorientation;

  • diarrhea; or

  • painful urination.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Demser?

Tell your doctor about all other medications you use, especially medicine to treat psychiatric disorders, such as:

This list is not complete and there may be other drugs that can interact with Demser. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide