Generic Name: crofelemer (kroe FEL e mer)
Brand Name: Fulyzaq, Mytesi
What is crofelemer?
Crofelemer is an anti-diarrheal medication that is used in adults with HIV or AIDS (human immunodeficiency virus or acquired immunodeficiency syndrome).
Crofelemer is used to treat diarrhea that is not caused by viral or bacterial infection (non-infectious). Crofelemer is given to people who are taking antiviral medications to treat HIV or AIDS.
Crofelemer is not a treatment for HIV or AIDS.
Crofelemer may also be used for purposes not listed in this medication guide.
What is the most important information I should know about crofelemer?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before taking crofelemer?
You should not use crofelemer if you are allergic to it.
To make sure crofelemer is safe for you, tell your doctor if you are sick with diarrhea and vomiting or other symptoms of infection.
FDA pregnancy category C. It is not known whether crofelemer will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether crofelemer passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Do not give this medication to anyone under 18 years old without medical advice.
How should I take crofelemer?
Before you start treatment with crofelemer, your doctor may perform medical tests to make sure you do not have infectious diarrhea.
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take crofelemer with or without food.
Do not crush, chew, or break a delayed-release tablet. Swallow it whole.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking crofelemer?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Crofelemer side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using crofelemer and call your doctor at once if you have:
dark urine, jaundice (yellowing of the skin or eyes);
wheezing, chest tightness, trouble breathing; or
Common side effects may include:
bloating, gas; or
cold symptoms such as stuffy nose, sneezing, cough.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Crofelemer dosing information
Usual Adult Dose for Diarrhea:
125 mg orally twice daily
Use: For symptomatic relief of noninfectious diarrhea in adult patients with HIV/AIDS on antiretroviral therapy:
What other drugs will affect crofelemer?
Other drugs may interact with crofelemer, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
See also: Side effects (in more detail)
More about crofelemer
- Side Effects
- During Pregnancy
- Dosage Information
- Support Group
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: antidiarrheals
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about crofelemer.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01.
Date modified: September 05, 2017
Last reviewed: May 13, 2013