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Buffered Salt

Generic name: potassium chloride and sodium chloridepoe-TAS-ee-um-and-SOE-dee-um-KLOR-ide ]
Brand names: Buffered Salt, Thermotabs
Drug class: Minerals and electrolytes

Medically reviewed by on Mar 28, 2023. Written by Cerner Multum.

What is Buffered Salt?

Potassium is a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart.

Sodium chloride is the chemical name for salt. Sodium is an electrolyte that regulates the amount of water in your body. Sodium also plays a part in nerve impulses and muscle contractions.

Buffered Salt is a combination mineral supplement that may be helpful in reducing tiredness, muscle cramps, or heat prostration that can occur when you sweat more than usual. This product is often used for outdoor recreational activities performed in high heat, or indoors anywhere high temperatures can cause you to become overheated.

It is not certain whether Buffered Salt is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. This medicine should not be used in place of medication prescribed for you by your doctor.

Buffered Salt may also be used for purposes not listed in this product guide.


Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Do not use this product without a doctor's advice if:

  • you have kidney disease; or

  • you are on a low-salt diet.

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have:

It is not known whether Buffered Salt will harm an unborn baby. Do not use this product without a doctor's advice if you are pregnant. Your dose needs may be different during pregnancy.

It is not known whether potassium chloride and sodium chloride passes into breast milk or if it could harm a nursing baby. Do not use this product without a doctor's advice if you are breast-feeding a baby.

Do not give any herbal/health supplement to a child without medical advice.

How should I take Buffered Salt?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

The usual dose of potassium chloride and sodium chloride is 1 tablet taken 5 to 10 times per day.

Take this product with a full glass of water.

You may need to adjust your dose based on the amount of heat to which you are exposed.

Call your doctor if the condition you are treating with Buffered Salt does not improve, or if it gets worse while using this product.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra Buffered Salt to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Buffered Salt?

Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity.

Buffered Salt side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Buffered Salt may cause serious side effects. Call your doctor at once if you have:

  • dehydration symptoms--hot and dry skin, feeling very thirsty or hot, confusion, being unable to urinate; or

  • high levels of potassium in your blood (hyperkalemia)--nausea, slow or unusual heart rate, muscle weakness, loss of movement.

Although not all side effects are known, Buffered Salt is thought to be likely safe for most people when used as directed.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Buffered Salt?

Do not take Buffered Salt without medical advice if you are using any of the following medications:

  • heart or blood pressure medication; or

  • cold or allergy medicine that contains an antihistamine (Benadryl and others).

This list is not complete. Other drugs may interact with potassium chloride and sodium chloride, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about Buffered Salt (potassium chloride / sodium chloride)

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.