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Acova

Generic Name: argatroban (ar GAT roe ban)
Brand Name: Acova

Medically reviewed on July 16, 2018

What is Acova?

Acova blocks the activity of certain clotting substances in the blood.

Acova is used to treat or prevent blood clots in adults who have thrombocytopenia (low levels of platelets in the blood) caused by using heparin. This medicine is sometimes used in people who are undergoing a procedure called angioplasty (to open blocked arteries).

Acova may also be used for purposes not listed in this medication guide.

Important Information

You should not use Acova if you have any major bleeding from a surgery, injury, or other cause.

Acova can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have unusual bruising, or bleeding that will not stop.

Before taking this medicine

You should not use Acova if you are allergic to it, or if you have any major bleeding from a surgery, injury, or other cause.

Tell your doctor if you have ever had:

Taking Acova during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant while taking this medicine.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Acova is not approved for use by anyone younger than 18 years old.

How is Acova given?

Acova is given as an infusion into a vein. A healthcare provider will give you this injection.

Acova is given until your blood coagulates properly. Your doctor will test your blood often to determine how long to treat you with this medicine.

Acova can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have unusual bruising, or bleeding that will not stop.

What happens if I miss a dose?

Since Acova is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

Since Acova is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Acova?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Avoid alcohol. It may increase your risk of bleeding in your stomach or intestines.

Acova side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • easy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding);

  • unexpected pain or swelling;

  • any bleeding that will not stop;

  • a light-headed feeling, like you might pass out;

  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • urine that looks red, pink, or brown;

  • slow heart rate, weak pulse, slow breathing; or

  • signs of infection--fever, flu symptoms, mouth and throat ulcers, pain or burning when you urinate, rapid heart rate, rapid and shallow breathing.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Acova?

Tell your doctor about all your other medicines, especially other medicines to treat or prevent blood clots.

Other drugs may affect Acova, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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