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How do you take Femara? What days do you take it?

Medically reviewed by Carmen Fookes, BPharm. Last updated on July 9, 2020.

Official Answer

by Drugs.com
  • For fertility issues and PCOS, Femara is typically taken once a day for five days.
  • Femara is usually started on day three or four of your monthly cycle (the first day of your monthly cycle is the first day of your period) and then taken for five days.
  • If you are taking Femara for breast cancer, it is usually taken once a day or once every other day.

Femara (letrozole) is a prescription medication used for the treatment of breast cancer and it is also commonly used off-label to treat ovulation problems including polycystic ovary syndrome (PCOS) and unexplained infertility.

For fertility issues and PCOS, Femara is typically taken once a day for five days. It is usually started on day three or four of your monthly cycle (the first day of your monthly cycle is the first day of your period) and then you ovulate about four to seven days after taking the last of the five pills. This means that if you started the pills on day one of your period then you should ovulate between days nine to twelve. Intercourse or intrauterine insemination (the artificial insertion of sperm) is timed to coincide with ovulation.

For breast cancer, Femara is usually taken once a day or once every other day.

References
  • Femara (letrozole) Novartis Pharmaceuticals Corporation https://www.drugs.com/pro/femara.html
  • Legro R, Brzyski R, Diamond M, et al. Letrozole versus Clomiphene for Infertility in the Polycystic Ovary Syndrome. N Engl J Med 2014; 371:119-129 DOI: 10.1056/NEJMoa1313517 Franik S,
  • Eltrop SM, Kremer JA, Kiesel L, Farquhar C. Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2018;5(5): CD010287. Published 2018 May 24. DOI:10.1002/14651858.CD010287.pub3

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