What is Ninlaro used for?
Ninlaro (ixazomib citrate) is a proteasome inhibitor used to treat patients with multiple myleoma. Multiple myeloma is a type of cancer of the bone marrow, which occurs when plasma cells grow uncontrolled.
Ninlaro comes in the from of a capsule. The Food and Drug Administration (FDA) has specifically approved Ninlaro for use in combination with a thalidomide analog called lenalidomide (Revlimid) and dexamethasone, a corticosteroid. Ninlaro is used in multiple myleoma patients who have received at least one prior therapy.
Ninlaro works by preventing the break down of all the 'garbage' proteins that myeloma cell generate, which leads to them building up and killing the myeloma cells.
Ninlaro is made by Takeda.
References
- Food and Drug Administration (FDA). Ninlaro. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208462s006lbl.pdf. [Accessed February 4, 2021].
- Multiple Myeloma Research Foundation (MMRF). Proteasome inhibitors. April 25, 2017. Available from: https://themmrf.org/2017/04/25/proteasome-inhibitors/. [Accessed February 4, 2021].
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Chemotherapy remains a cornerstone in managing multiple myeloma, a cancer of plasma cells in the bone marrow. While newer therapies like immunomodulators and proteasome inhibitors have expanded treatment options, chemotherapy continues to play a vital role—particularly when combined with other approaches.
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What are the best treatments for Multiple Myeloma?
Multiple myeloma is a cancer of plasma cells, which are white blood cells responsible for producing antibodies. While not yet curable, advancements in therapy have transformed it into a manageable condition with treatments that can achieve long-term disease control and improved quality of life. Initial treatment usually involves multi-drug combinations, such as bortezomib (a proteasome inhibitor), lenalidomide (an immunomodulatory drug), and dexamethasone (a steroid).
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Is Velcade a type of chemotherapy?
Velcade is not a traditional form of chemotherapy (chemo). Velcade is a targeted drug therapy in the class of drugs known as proteasome inhibitors. Continue reading
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Drug information
- Ninlaro Information for Consumers
- Ninlaro prescribing info & package insert (for Health Professionals)
- Side Effects of Ninlaro (detailed)
- Ninlaro user reviews (3)
Related support groups
- Ninlaro (6 questions, 5 members)
- Multiple Myeloma (24 questions, 54 members)