Does Tezspire cause weight gain?
Weight gain is not a common side effect of Tezspire (tezepelumab-ekko). In two 52-week clinical trials, weight gain wasn’t reported as a side effect. Additionally, weight gain has not been reported in postmarketing monitoring.
Talk to your doctor if you have unexpected weight gain during your treatment with Tezspire. Gaining too much weight can lead to serious health problems, such as diabetes and heart disease.
Tezspire is a thymic stromal lymphopoietin (TSLP) blocker. It’s used for add-on maintenance treatment of severe asthma in adults and children 12 years and older. It is injected under the skin once a month. It was FDA approved in December 2021.
References
Corren, J., et. al. (2023). Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials. In: American Journal of Respiratory and Critical Care Medicine. Accessed on 05/31/24 at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870853/
Tezspire [package insert]. (Revised May 2023). Amgen, Inc. Accessed 05/31/24 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=60f0aa03-ad25-4d48-80ce-7fcfa76f325f
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What are 5 key Tezspire side effects to watch out for?
Common side effects of Tezspire include sore throat, joint pain, back pain, and injection-site reactions. Rarely, severe allergic reactions can happen hours or days after getting a dose of Tezspire. Continue reading
How do I use the Tezspire pen?
Your healthcare provider can show you how to self-administer the Tezspire pen. Do not attempt to administer it yourself until you have received full instructions. Take it out of the refrigerator, and leave it in the carton and allow it to come to room temperature between 68°F to 77˚F (20°C to 25°C) for about 60 minutes before giving the injection. Do not remove the cap just yet. Continue reading
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Drug information
- Tezspire Information for Consumers
- Tezspire prescribing info & package insert (for Health Professionals)
- Side Effects of Tezspire (detailed)
- Tezspire user reviews (35)
Related support groups
- Tezspire (4 questions, 4 members)
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