How is Rituxan Hycela administered?
Rituxan Hycela (rituximab and hyaluronidase human) is given via subcutaneous injection - an injection under the skin - in the stomach area. It is administered by a healthcare professional.
Rituxan Hycela contains rituximab, the same active ingredient as in Rituxan. But it has been formulated so that it can be given over 5-7 minutes via subcutaneous injection, rather than via intravenous (IV) infusion like Rituxan, which can take 3-6 hours.
Rituxan Hycela should only be administered after at least one full dose of a rituximab product has been administered via intravenous (IV) infusion because of the potential for hypersensitivity reactions and other side effects during the initial administration of rituximab products.
Before you receive Rituxan Hycela, an antihistamine and acetaminophen, and possibly a glucocorticoid medication, will be administered to help prevent side effects. After your injection you’ll be monitored for at least 15 minutes.
References
- Rituxan Hycela website. Prescribing information. Administration. [Accessed September 29, 20201]. Available from: https://www.rituxanhycela.com/hcp/dosing-and-administration/administration.html.
- NIH, National Cancer Institute. New Rituximab Formulation Approved for Some Lymphomas, Leukemia. July 14, 2017. [Accessed September 29, 2021]. Available from: https://www.cancer.gov/news-events/cancer-currents-blog/2017/fda-rituxan-hycela.
Read next
What is the difference between Rituxan and Rituxan Hycela?
Rituxan (rituximab) is administered intravenously (IV), while Rituxan Hycela is given subcutaneously (SC). Continue reading
How will I feel after a Rituxan infusion?
After a Rituxan (rituximab) infusion you may experience certain side effects or adverse reactions that make you feel unwell. Common side effects include nausea, infusion-related reactions, and feeling tired. Continue reading
How long does it take for Rituxan to work?
Patients treated with Rituxan may notice an early response within 7-8 weeks of treatment. Most rheumatoid arthritis patients will notice some improvement in their symptoms, such as improvement in their levels of pain and inflammation, within 16 weeks of starting treatment with Rituxan. Continue reading
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Drug information
- Rituxan Hycela Information for Consumers
- Rituxan Hycela prescribing info & package insert (for Health Professionals)
- Side Effects of Rituxan Hycela (detailed)
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